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Two-photon endomicroscopy with microsphere-spliced double-cladding antiresonant fiber for resolution enhancement

  • Conghao Wang
  • , Huilan Liu
  • , Haodong Cui
  • , Jianrui Ma
  • , Yijun Li
  • , Jingquan Tian
  • , Chaoyong Jin
  • , Yanchuan Chen
  • , Yuqian Gao
  • , Qiang Fu
  • , Yanhui Hu
  • , Dakun Wu
  • , Fei Yu
  • , Runlong Wu
  • , Aimin Wang
  • , Lishuang Feng*
  • *此作品的通讯作者
  • Beihang University
  • Ltd
  • LUSTER LightTech Co. Ltd.
  • University of Chinese Academy of Sciences
  • CAS - Shanghai Institute of Optics and Fine Mechanics
  • Peking University

科研成果: 期刊稿件文章同行评审

摘要

We demonstrate a miniature fiber-optic two two-photon endomicroscopy with microsphere-spliced double-cladding antiresonant fiber for resolution enhancement. An easy-tooperate process for fixing microsphere permanently in an antiresonant fiber core, by arc discharge, is proposed. The flexible fiber-optic probe is integrated with a parameter of 5.8mm× 49.1mm (outer diameter × rigid length); the field of view is 210 μm, the resolution is 1.3 μm, and the frame rate is 0.7 fps. The imaging ability is verified using ex-vivo mouse kidney, heart, stomach, tail tendon, and in-vivo brain neural imaging.

源语言英语
页(从-至)26090-26101
页数12
期刊Optics Express
30
15
DOI
出版状态已出版 - 18 7月 2022

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