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The mutual information of attractors in scale-free boolean networks

科研成果: 书/报告/会议事项章节会议稿件同行评审

摘要

Boolean Network, originally developed by Kauffman in 1969, is one of the models to study genetic regulatory networks, and it has been widely applied in Bioscience. In this paper, we proposed a model of Boolean Networks in which the topological structures and updating functions were different from the classical random graph model. For topological structures, the output degree of a node obeyed power law distribution, while the input of each node remained fixed as the classical N-K model. For updating functions, two parameters '1 and '2 were used to generate various Boolean functions. By calculating the mutual information and robustness of attractors in instances of Scale-free Boolean Networks, we investigated the relationships between structure parameters and rule parameters, which were involved in different phase with respect to different parameters. Furthermore, we observed that the structure parameters determined the regions that robustness '... and mutual information belonged to, while rule parameters 1 and '2 determined the relative values of R and L.

源语言英语
主期刊名ICBCI 2017 - Proceedings of 2017 International Conference on Bioinformatics and Computational Intelligence
出版商Association for Computing Machinery
36-39
页数4
ISBN(电子版)9781450353113
DOI
出版状态已出版 - 8 9月 2017
活动2017 International Conference on Bioinformatics and Computational Intelligence, ICBCI 2017 - Beijing, 中国
期限: 8 9月 201711 9月 2017

出版系列

姓名ACM International Conference Proceeding Series

会议

会议2017 International Conference on Bioinformatics and Computational Intelligence, ICBCI 2017
国家/地区中国
Beijing
时期8/09/1711/09/17

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