@inproceedings{4c1ea8adfe7a434f8e0f7719643fefb9,
title = "The Dynamic Spatiotemporal Features Based on Rich Club Organization in Autism Spectrum Disorder",
abstract = "The dynamic operational mechanisms of the brain in autism spectrum disorder (ASD) remain unclear. In this study, utilizing resting-state functional magnetic resonance imaging (fMRI) technology, we aimed to analyze the spatiotemporal characteristics of brain networks based on the rich club Organization, extracting time-varying features in individuals with ASD. We evaluated differences in spatiotemporal similarity of dynamic brain networks between ASD patients and healthy controls (HC). Results revealed unstable composition of the rich club in ASD patients over time, with weaker spatiotemporal similarity compared to healthy controls. Furthermore, employing spatiotemporal transformation features based on network topology, we classified ASD patients and healthy controls. Our findings demonstrate higher classification accuracy using time-varying features compared to static brain network topology features. This study enhances our understanding of the dynamic brain network mechanisms in ASD and suggests reliable methods for early diagnosis.",
keywords = "Dynamic Brain Networks, Rich Club, Spatiotemporal Features, fMRI",
author = "Chang Liu and Tao Liu and Jingye Sheng and Jikun Zheng and Pengcheng Huang and Bin Wang",
note = "Publisher Copyright: {\textcopyright} The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2024.; 20th International Symposium on Bioinformatics Research and Applications, ISBRA 2024 ; Conference date: 19-07-2024 Through 21-07-2024",
year = "2024",
doi = "10.1007/978-981-97-5131-0\_17",
language = "英语",
isbn = "9789819751303",
series = "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
publisher = "Springer Science and Business Media Deutschland GmbH",
pages = "189--201",
editor = "Wei Peng and Zhipeng Cai and Pavel Skums",
booktitle = "Bioinformatics Research and Applications - 20th International Symposium, ISBRA 2024, Proceedings",
address = "德国",
}