Synthesis of the biomimetic polymer: Aliphatic diamine and RGDS modified poly (d,l-lactic acid)

Xu Feng Niu; Yuan Liang Wang; Yan Feng Luo; Jun Pan; Juan Fang Shang; Li Xia Guo

Synthesis of the biomimetic polymer: Aliphatic diamine and RGDS modified poly (d,l-lactic acid)

Xu Feng Niu^*
, Yuan Liang Wang
, Yan Feng Luo
, Jun Pan
, Juan Fang Shang
, Li Xia Guo

^*此作品的通讯作者

Chongqing University

科研成果: 期刊稿件 › 文章 › 同行评审

13 引用（Scopus）

摘要

A novel poly(d, l-lactic acid) (PDLLA) based biomimetic polymer was synthesized by grafting maleic anhydride, butanediamine and arg-gly-asp-ser (RGDS) peptides onto the backbone of PDLLA, aiming to overcome the acidity and auto-accelerating degradation of PDLLA during degradation and to improve its biospecificity and biocompatibility. The synthetic copolymer was characterized by FTIR, ¹³C NMR and amino acid analyzer (AAA).

源语言	英语
页（从-至）	1035-1038
页数	4
期刊	Chinese Chemical Letters
卷	16
期	8
出版状态	已出版 - 8月 2005
已对外发布	是

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@article{01c04c0e83214fada61f9a38b06b75b7,

title = "Synthesis of the biomimetic polymer: Aliphatic diamine and RGDS modified poly (d,l-lactic acid)",

abstract = "A novel poly(d, l-lactic acid) (PDLLA) based biomimetic polymer was synthesized by grafting maleic anhydride, butanediamine and arg-gly-asp-ser (RGDS) peptides onto the backbone of PDLLA, aiming to overcome the acidity and auto-accelerating degradation of PDLLA during degradation and to improve its biospecificity and biocompatibility. The synthetic copolymer was characterized by FTIR, 13C NMR and amino acid analyzer (AAA).",

keywords = "Butanediamine, Maleic anhydride, Modification, Poly(d, l-lactic acid), arg-gly-asp-ser",

author = "Niu, \{Xu Feng\} and Wang, \{Yuan Liang\} and Luo, \{Yan Feng\} and Jun Pan and Shang, \{Juan Fang\} and Guo, \{Li Xia\}",

year = "2005",

month = aug,

language = "英语",

volume = "16",

pages = "1035--1038",

journal = "Chinese Chemical Letters",

issn = "1001-8417",

publisher = "Elsevier B.V.",

number = "8",

}

TY - JOUR

T1 - Synthesis of the biomimetic polymer

T2 - Aliphatic diamine and RGDS modified poly (d,l-lactic acid)

AU - Niu, Xu Feng

AU - Wang, Yuan Liang

AU - Luo, Yan Feng

AU - Pan, Jun

AU - Shang, Juan Fang

AU - Guo, Li Xia

PY - 2005/8

Y1 - 2005/8

N2 - A novel poly(d, l-lactic acid) (PDLLA) based biomimetic polymer was synthesized by grafting maleic anhydride, butanediamine and arg-gly-asp-ser (RGDS) peptides onto the backbone of PDLLA, aiming to overcome the acidity and auto-accelerating degradation of PDLLA during degradation and to improve its biospecificity and biocompatibility. The synthetic copolymer was characterized by FTIR, 13C NMR and amino acid analyzer (AAA).

AB - A novel poly(d, l-lactic acid) (PDLLA) based biomimetic polymer was synthesized by grafting maleic anhydride, butanediamine and arg-gly-asp-ser (RGDS) peptides onto the backbone of PDLLA, aiming to overcome the acidity and auto-accelerating degradation of PDLLA during degradation and to improve its biospecificity and biocompatibility. The synthetic copolymer was characterized by FTIR, 13C NMR and amino acid analyzer (AAA).

KW - Butanediamine

KW - Maleic anhydride

KW - Modification

KW - Poly(d, l-lactic acid)

KW - arg-gly-asp-ser

UR - https://www.scopus.com/pages/publications/33745049026

M3 - 文章

AN - SCOPUS:33745049026

SN - 1001-8417

VL - 16

SP - 1035

EP - 1038

JO - Chinese Chemical Letters

JF - Chinese Chemical Letters

IS - 8

ER -

Synthesis of the biomimetic polymer: Aliphatic diamine and RGDS modified poly (d,l-lactic acid)

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