TY - JOUR
T1 - Schottky nanodiodes array enabled triboelectric nanosecond pulse generator for ultralow-cost tumor therapy
AU - Xu, Lingling
AU - Wang, Engui
AU - Kang, Yong
AU - Fu, Dianxun
AU - Luo, Lin
AU - Quan, Yichang
AU - Xi, Yuan
AU - Huang, Jing
AU - Cui, Xi
AU - Zeng, Jia
AU - Jiang, Dongjie
AU - Shi, Bojing
AU - Feng, Hongqing
AU - Ouyang, Han
AU - Chen, Chunying
AU - Li, Zhou
N1 - Publisher Copyright:
© 2025 The Author(s)
PY - 2025/6/20
Y1 - 2025/6/20
N2 - Generating reliable high-voltage nanosecond pulses (hvNPs) is challenging in terms of materials, electronics, and power supply. Inspired by the natural phenomenon of lightning, we report a Schottky nanodiode array-enabled triboelectric nanosecond pulse generator (st-NPG) that eliminates the need for an external electrical power supply or boosting circuits, relying instead on mechanical energy input to directly generate hvNPs. This st-NPG, with high voltage (10 kV), peak power (17 MW), single-pulse energy (0.6 J), and stability (7 days of operation), is enabled by a capacitive wafer-scale semiconductor titanium dioxide (TiO2) nanotube array with substantial charge storage and trapping capabilities. The st-NPG also enabled pulsed ablation for tumor treatment in mice and rabbits via minimally invasive interventional surgery. The ultracheap (<1/1,000 of commercial cost), power-source-free st-NPG should open opportunities for healthcare, environmental protection, science, and education applications around the world, especially in resource-poor regions.
AB - Generating reliable high-voltage nanosecond pulses (hvNPs) is challenging in terms of materials, electronics, and power supply. Inspired by the natural phenomenon of lightning, we report a Schottky nanodiode array-enabled triboelectric nanosecond pulse generator (st-NPG) that eliminates the need for an external electrical power supply or boosting circuits, relying instead on mechanical energy input to directly generate hvNPs. This st-NPG, with high voltage (10 kV), peak power (17 MW), single-pulse energy (0.6 J), and stability (7 days of operation), is enabled by a capacitive wafer-scale semiconductor titanium dioxide (TiO2) nanotube array with substantial charge storage and trapping capabilities. The st-NPG also enabled pulsed ablation for tumor treatment in mice and rabbits via minimally invasive interventional surgery. The ultracheap (<1/1,000 of commercial cost), power-source-free st-NPG should open opportunities for healthcare, environmental protection, science, and education applications around the world, especially in resource-poor regions.
KW - DTI-3: Develop
KW - Schottky contact
KW - contact electrification
KW - electrical stimulation
KW - high-voltage nanosecond pulses
KW - irreversible electroporation
KW - nanosecond pulsed electric field
KW - triboelectric nanogenerator
KW - tumor ablation
UR - https://www.scopus.com/pages/publications/105008233387
U2 - 10.1016/j.device.2025.100721
DO - 10.1016/j.device.2025.100721
M3 - 文章
AN - SCOPUS:105008233387
SN - 2666-9986
VL - 3
JO - Device
JF - Device
IS - 6
M1 - 100721
ER -