Research on Raman Imaging Technology Based on Surface Enhanced Raman Scattering

Raman scattering originates from the change of relative position between atoms in molecules or crystals, that is, vibration and rotation. It is an important analytical method to study the structure of molecules and solid materials. Compared with other analytical methods, Raman spectroscopy has been widely used in many fields such as chemistry, physics, materials science, life science, environmental science, medicine, geology, cultural relics archaeology, public security law and so on, because of its unique advantages such as abundant information, simple sample preparation and no damage to samples. In this paper, the principle and enhancement mechanism of SERS (Surface Enhanced Raman Scattering) are discussed, the Raman imaging technology based on SERS is introduced, and its applications in different imaging fields are discussed in detail. Finally, the existing problems of SERS biological imaging technology are discussed, and the research and application prospects of this technology are prospected.