TY - JOUR
T1 - Preparation of molecularly imprinted microspheres by photo-grafting on supports modified with iniferter
AU - Rong, Fei
AU - Feng, Xiaogang
AU - Li, Ping
AU - Yuan, Chunwei
AU - Fu, Degang
PY - 2006/11
Y1 - 2006/11
N2 - Molecularly imprinted microspheres (MIMs) of D-mandelic acid were synthesized in this study. Chloromethylated polystyrene beads modified with iniferter were used as supports for photo-grafting of a molecularly imprinted polymer (MIP) layer. The polymers were characterized by FT-IR, elemental analysis and thermo-gravimetric analysis to testify the polymer formation and its thermal stability. Scanning electron micrographs (SEM) show that the MIP particles are mono-dispersed and well-spherical, with the average diameter of 4.38 μm and size distribution coefficient of 1.02. Furthermore, the MIMs were packed in a stainless steel column and evaluated as stationary phases in high performance liquid chromatography (HPLC). The prepared MIP exhibited a considerable capability of chiral separation between template and its enantiomer. Accordingly, this kind of MIP is likely to have wide applications in chemical sensing, chromatographic analysis and solid phase extraction.
AB - Molecularly imprinted microspheres (MIMs) of D-mandelic acid were synthesized in this study. Chloromethylated polystyrene beads modified with iniferter were used as supports for photo-grafting of a molecularly imprinted polymer (MIP) layer. The polymers were characterized by FT-IR, elemental analysis and thermo-gravimetric analysis to testify the polymer formation and its thermal stability. Scanning electron micrographs (SEM) show that the MIP particles are mono-dispersed and well-spherical, with the average diameter of 4.38 μm and size distribution coefficient of 1.02. Furthermore, the MIMs were packed in a stainless steel column and evaluated as stationary phases in high performance liquid chromatography (HPLC). The prepared MIP exhibited a considerable capability of chiral separation between template and its enantiomer. Accordingly, this kind of MIP is likely to have wide applications in chemical sensing, chromatographic analysis and solid phase extraction.
KW - Iniferter
KW - Molecularly imprinted microspheres
KW - Photo-grafting
KW - Polystyrene beads
UR - https://www.scopus.com/pages/publications/33751291413
U2 - 10.1007/s11434-006-2170-5
DO - 10.1007/s11434-006-2170-5
M3 - 文章
AN - SCOPUS:33751291413
SN - 1001-6538
VL - 51
SP - 2566
EP - 2571
JO - Chinese Science Bulletin
JF - Chinese Science Bulletin
IS - 21
ER -