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Mining the bioinformation of differentially expressed genes in lung treated with the hypoxia based on the bioinformatics methods

  • Cuihong Zhou
  • , Xiaoyan Deng
  • , Jun Zhou
  • , De Bi
  • , Huajun Xiao*
  • *此作品的通讯作者
  • Beihang University

科研成果: 书/报告/会议事项章节会议稿件同行评审

摘要

Objective: To analyze the differentially expressed genes expressed genes in human pulmonary microvascular endothelial cells (HMVEC-L) that cultured in hypoxia environment for getting better understanding of the molecular characteristics caused by hypoxia. Methods: Got the microarray hybridization data from the Gene Expression Omnibus (GEO) database. Identified the differentially expressed genes expressed genes in hypoxic HMVEC-L and the patterns of their regulation using public bioinformatics software and database, which involved BRB-Arraytools, Genecodis, GO and KEGG. Results and Conclusion: These data mining findings between normal and hypoxic HMVEC-L by bioinformatics methods could provide better understanding of the molecular activity change caused by hypoxia.

源语言英语
主期刊名5th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2011
DOI
出版状态已出版 - 2011
活动5th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2011 - Wuhan, 中国
期限: 10 5月 201112 5月 2011

出版系列

姓名5th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2011

会议

会议5th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2011
国家/地区中国
Wuhan
时期10/05/1112/05/11

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