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MEG source imaging algorithm for finding deeper epileptogenic zone

  • Yegang Hu
  • , Yicong Lin
  • , Baoshan Yang
  • , Guangrui Tang
  • , Yuping Wang
  • , Jicong Zhang*
  • *此作品的通讯作者
  • Beihang University
  • Capital Medical University

科研成果: 书/报告/会议事项章节会议稿件同行评审

摘要

In recent years, magnetoencephalography (MEG) has played a prominent role on neocortical epilepsy preoperative evaluation. However, its clinical utility with locating deeper sources may be more challenging such as the mesial temporal structures. We proposed a new source imaging algorithm for finding the epileptogenic zone in mesial temporal lobe epilepsy (mTLE). Since the localization results using the Elekta MEG method are very sensitive to some MEG noises, the source modeling was modified by spatial filtering in wavelet domain and cortex constraint. Two surgical patients randomly selected with medically refractory mTLE, which were diagnosed based on a comprehensive preoperative evaluation, had been studied in this manuscript. The localization results using proposed method on individual MRI showed that the deeper regions had been exactly found in the mesial temporal lobe. Yet, the results using the Elekta Neuromag Software only appeared in the lateral temporal lobe. Thus, the proposed algorithm maybe become an effective method in detecting deeper epileptogenic zone.

源语言英语
主期刊名Advanced Computational Methods in Life System Modeling and Simulation - International Conference on Life System Modeling and Simulation, LSMS 2017 and International Conference on Intelligent Computing for Sustainable Energy and Environment, ICSEE 2017, Proceedings
编辑Minrui Fei, Shiwei Ma, Xin Li, Xin Sun, Li Jia, Zhou Su
出版商Springer Verlag
536-544
页数9
ISBN(印刷版)9789811063695
DOI
出版状态已出版 - 2017
活动International Conference on Life System Modeling and Simulation, LSMS 2017 and International Conference on Intelligent Computing for Sustainable Energy and Environment, ICSEE 2017 - Nanjing, 中国
期限: 22 9月 201724 9月 2017

出版系列

姓名Communications in Computer and Information Science
761
ISSN(印刷版)1865-0929

会议

会议International Conference on Life System Modeling and Simulation, LSMS 2017 and International Conference on Intelligent Computing for Sustainable Energy and Environment, ICSEE 2017
国家/地区中国
Nanjing
时期22/09/1724/09/17

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