Label-free quantitative imaging of cholesterol in intact tissues by hyperspectral stimulated Raman scattering microscopy

Ping Wang; Junjie Li; Pu Wang; Chun Rui Hu; Delong Zhang; Michael Sturek; Ji Xin Cheng

doi:10.1002/anie.201306234

Label-free quantitative imaging of cholesterol in intact tissues by hyperspectral stimulated Raman scattering microscopy

Ping Wang
, Junjie Li
, Pu Wang
, Chun Rui Hu
, Delong Zhang
, Michael Sturek^*
, Ji Xin Cheng

^*此作品的通讯作者

Purdue University
Indiana University Bloomington

科研成果: 期刊稿件 › 文章 › 同行评审

101 引用（Scopus）

摘要

A finger on the pulse: Current molecular analysis of cells and tissues routinely relies on separation, enrichment, and subsequent measurements by various assays. Now, a platform of hyperspectral stimulated Raman scattering microscopy has been developed for the fast, quantitative, and label-free imaging of biomolecules in intact tissues using spectroscopic fingerprints as the contrast mechanism.

源语言	英语
页（从-至）	13042-13046
页数	5
期刊	Angewandte Chemie - International Edition
卷	52
期	49
DOI	https://doi.org/10.1002/anie.201306234
出版状态	已出版 - 2 12月 2013
已对外发布	是

访问文件

10.1002/anie.201306234

其它文件与链接

链接到 Scopus 的出版物

引用此

@article{41a9f95351db4184af93c9257d7544c1,

title = "Label-free quantitative imaging of cholesterol in intact tissues by hyperspectral stimulated Raman scattering microscopy",

abstract = "A finger on the pulse: Current molecular analysis of cells and tissues routinely relies on separation, enrichment, and subsequent measurements by various assays. Now, a platform of hyperspectral stimulated Raman scattering microscopy has been developed for the fast, quantitative, and label-free imaging of biomolecules in intact tissues using spectroscopic fingerprints as the contrast mechanism.",

keywords = "cholesterol, lipids, stimulated Raman scattering, tissue analysis, vibrational spectroscopy",

author = "Ping Wang and Junjie Li and Pu Wang and Hu, \{Chun Rui\} and Delong Zhang and Michael Sturek and Cheng, \{Ji Xin\}",

year = "2013",

month = dec,

day = "2",

doi = "10.1002/anie.201306234",

language = "英语",

volume = "52",

pages = "13042--13046",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

publisher = "John Wiley and Sons Ltd",

number = "49",

}

TY - JOUR

T1 - Label-free quantitative imaging of cholesterol in intact tissues by hyperspectral stimulated Raman scattering microscopy

AU - Wang, Ping

AU - Li, Junjie

AU - Wang, Pu

AU - Hu, Chun Rui

AU - Zhang, Delong

AU - Sturek, Michael

AU - Cheng, Ji Xin

PY - 2013/12/2

Y1 - 2013/12/2

N2 - A finger on the pulse: Current molecular analysis of cells and tissues routinely relies on separation, enrichment, and subsequent measurements by various assays. Now, a platform of hyperspectral stimulated Raman scattering microscopy has been developed for the fast, quantitative, and label-free imaging of biomolecules in intact tissues using spectroscopic fingerprints as the contrast mechanism.

AB - A finger on the pulse: Current molecular analysis of cells and tissues routinely relies on separation, enrichment, and subsequent measurements by various assays. Now, a platform of hyperspectral stimulated Raman scattering microscopy has been developed for the fast, quantitative, and label-free imaging of biomolecules in intact tissues using spectroscopic fingerprints as the contrast mechanism.

KW - cholesterol

KW - lipids

KW - stimulated Raman scattering

KW - tissue analysis

KW - vibrational spectroscopy

UR - https://www.scopus.com/pages/publications/84888599621

U2 - 10.1002/anie.201306234

DO - 10.1002/anie.201306234

M3 - 文章

C2 - 24127161

AN - SCOPUS:84888599621

SN - 1433-7851

VL - 52

SP - 13042

EP - 13046

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 49

ER -

Label-free quantitative imaging of cholesterol in intact tissues by hyperspectral stimulated Raman scattering microscopy

摘要

访问文件

其它文件与链接

学术指纹

引用此