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Interaction-aware dexterous robot for minimally invasive transcanal inner ear interventions

  • Haiming Li
  • , Peiyuan Gao
  • , Haoyue Tan
  • , Haotian Li
  • , Haifeng Zhu
  • , Mengyuan Jiang
  • , Yuting Ni
  • , Yandi He
  • , Junhong Huang
  • , Yue Zhu
  • , Jiahui Yang
  • , Chunbo Wang
  • , Bin Liu
  • , Fuxin Du
  • , Yanhe Zhu
  • , Huijuan Dong
  • , He Zhang*
  • , Tianxue Zhang*
  • , Huan Jia*
  • , Hao Wu
  • Jie Zhao
*此作品的通讯作者
  • Harbin Institute of Technology
  • Department of Otolaryngology-Head and Neck Surgery
  • Shanghai Jiao Tong University
  • Shanghai Key Laboratory of Translational Medicine on Ear and Nose Diseases
  • Beihang University
  • School of Biomedical Engineering
  • Sun Yat-Sen University
  • Shandong University

科研成果: 期刊稿件 › 文章 › 同行评审

摘要

Intracochlear theranostics, particularly targeted drug delivery and microsampling, offers a promising solution to inner ear diseases. However, specialized medical devices remain limited by a fundamental design challenge imposed by anatomical constraints: balancing miniaturization, dexterity, and perceptive functionality. Here, we present a low–aspect-ratio, dual-segment continuum robot that integrates catheter, endoscopic and instrumental functions. Driven by antagonistic cables, the robot uses a transition-free backbone composed of saddle-shaped joints to achieve a minimum bending radius of 1.9 mm. Dual-segment motion decoupling yields programmable C-/S-shaped configurations, facilitating anatomical navigation. The microneedle, embedded in the central channel, serves as an end-effector with positioning accuracy of 17.9 ± 4.1 μm. Fiber Bragg grating sensors, mounted on the needle, measure axial force to estimate tool-tissue interaction. Validation is performed on cadavers and in vivo animals, demonstrating the feasibility of a transcanal, atraumatic robotic paradigm. Thus, this system provides a practical and accessible approach for early diagnosis and treatment, helping extend precision medicine to underserved areas.

源语言英语
期刊论文编号5658
期刊Nature Communications
卷17
期1
DOI
出版状态已出版 - 12月 2026

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