TY - JOUR
T1 - Influence of endoleak positions on the pressure shielding ability of stent-graft after endovascular aneurysm repair (EVAR) of abdominal aortic aneurysm (AAA)
AU - Li, Jie
AU - Tian, Xiaopeng
AU - Wang, Zhenze
AU - Xiong, Jiang
AU - Fan, Yubo
AU - Deng, Xiaoyan
AU - Sun, Anqiang
AU - Liu, Xiao
N1 - Publisher Copyright:
© 2016 The Author(s).
PY - 2016/12/28
Y1 - 2016/12/28
N2 - Background: Abdominal aortic aneurysm (AAA) is a kind of dangerous aortic vascular disease, which is characterized by abdominal aorta partial enlargement. At present, endovascular aneurysm repair (EVAR) is one of the main treatments of abdominal aortic aneurysm. However for some patients after EVAR the aneurysm re-expanded and even ruptured, leading to poor postoperative effect. The stent-graft endoleak after EVAR was realized to influence the AAA in-sac pressure and contribute to the aneurysm re-enlargement. Methods: In order to analyze the influence of endoleaks positions on the pressure shielding ability of stent-graft after EVAR, type I and type III endoleak models were reconstructed based on computed tomography (CT) scan images, and the hemodynamic environment in AAA was numerically simulated. Results: When the endoleak was at the proximal position the pressure shielding ability will be obviously weakened. While, the pressure shielding ability was higher in the systole phase than that in diastole phase when the endoleak located at the middle or distal positions. Unfortunately, when the endoleak located at the proximal position, the pressure shielding ability would be relatively weak in the whole cardiac cycle. Conclusions: The results revealed that the influence of endoleaks on pressure shielding ability of stent-graft was both location and time specific.
AB - Background: Abdominal aortic aneurysm (AAA) is a kind of dangerous aortic vascular disease, which is characterized by abdominal aorta partial enlargement. At present, endovascular aneurysm repair (EVAR) is one of the main treatments of abdominal aortic aneurysm. However for some patients after EVAR the aneurysm re-expanded and even ruptured, leading to poor postoperative effect. The stent-graft endoleak after EVAR was realized to influence the AAA in-sac pressure and contribute to the aneurysm re-enlargement. Methods: In order to analyze the influence of endoleaks positions on the pressure shielding ability of stent-graft after EVAR, type I and type III endoleak models were reconstructed based on computed tomography (CT) scan images, and the hemodynamic environment in AAA was numerically simulated. Results: When the endoleak was at the proximal position the pressure shielding ability will be obviously weakened. While, the pressure shielding ability was higher in the systole phase than that in diastole phase when the endoleak located at the middle or distal positions. Unfortunately, when the endoleak located at the proximal position, the pressure shielding ability would be relatively weak in the whole cardiac cycle. Conclusions: The results revealed that the influence of endoleaks on pressure shielding ability of stent-graft was both location and time specific.
KW - Abdominal aortic aneurysm
KW - Endoleak
KW - Pressure shielding ability
UR - https://www.scopus.com/pages/publications/85007130700
U2 - 10.1186/s12938-016-0249-z
DO - 10.1186/s12938-016-0249-z
M3 - 文章
C2 - 28155691
AN - SCOPUS:85007130700
SN - 1475-925X
VL - 15
JO - BioMedical Engineering Online
JF - BioMedical Engineering Online
M1 - 135
ER -