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Hemodynamic impact of snoring on carotid artery after stent implantation: the role of oscillation

  • Xianghao Zhang
  • , Zhenmin Fan*
  • , Xiao Liu
  • , Mingyuan Liu
  • , Xia Ye*
  • , Xiaoyan Deng
  • *此作品的通讯作者
  • Jiangsu University of Technology
  • Capital Medical University

科研成果: 期刊稿件文章同行评审

摘要

Snoring is common in overweight and elderly patients treated by endovascular stenting. Studies have proved a correlation between snoring and carotid stenosis, thus, snoring after carotid artery stenting (CAS) might promote or worsen clinical performance. This study tested this hypothesis by constructing a patient-specific carotid bifurcation model and numerically analyzing hemodynamic changes of the carotid artery under different snoring conditions. These conditions included small and large amplitude, low and high frequency, and different age groups. The results found that high amplitude snoring suppressed the disturbed flow at the stented segment while the down-stream region of ICA became more chaotic, accounting for in-stent intimal restenosis and thrombosis. Furthermore, local blood flow patterns of elder groups with snoring symptoms were more likely to be changed due to low-speed flow, increasing the possibility of vascular remodeling and thrombosis. Besides, increased snoring frequency hardly influenced the local disturbed flow. Therefore, older adults should receive medical treatment actively after stenting for high-amplitude snoring as soon as possible to avoid potential adverse events.

源语言英语
页(从-至)35-45
页数11
期刊Acta of Bioengineering and Biomechanics
25
1
DOI
出版状态已出版 - 2023

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