TY - JOUR
T1 - Hemodynamic impact of snoring on carotid artery after stent implantation
T2 - the role of oscillation
AU - Zhang, Xianghao
AU - Fan, Zhenmin
AU - Liu, Xiao
AU - Liu, Mingyuan
AU - Ye, Xia
AU - Deng, Xiaoyan
N1 - Publisher Copyright:
© 2023, Institute of Machine Design and Operation. All rights reserved.
PY - 2023
Y1 - 2023
N2 - Snoring is common in overweight and elderly patients treated by endovascular stenting. Studies have proved a correlation between snoring and carotid stenosis, thus, snoring after carotid artery stenting (CAS) might promote or worsen clinical performance. This study tested this hypothesis by constructing a patient-specific carotid bifurcation model and numerically analyzing hemodynamic changes of the carotid artery under different snoring conditions. These conditions included small and large amplitude, low and high frequency, and different age groups. The results found that high amplitude snoring suppressed the disturbed flow at the stented segment while the down-stream region of ICA became more chaotic, accounting for in-stent intimal restenosis and thrombosis. Furthermore, local blood flow patterns of elder groups with snoring symptoms were more likely to be changed due to low-speed flow, increasing the possibility of vascular remodeling and thrombosis. Besides, increased snoring frequency hardly influenced the local disturbed flow. Therefore, older adults should receive medical treatment actively after stenting for high-amplitude snoring as soon as possible to avoid potential adverse events.
AB - Snoring is common in overweight and elderly patients treated by endovascular stenting. Studies have proved a correlation between snoring and carotid stenosis, thus, snoring after carotid artery stenting (CAS) might promote or worsen clinical performance. This study tested this hypothesis by constructing a patient-specific carotid bifurcation model and numerically analyzing hemodynamic changes of the carotid artery under different snoring conditions. These conditions included small and large amplitude, low and high frequency, and different age groups. The results found that high amplitude snoring suppressed the disturbed flow at the stented segment while the down-stream region of ICA became more chaotic, accounting for in-stent intimal restenosis and thrombosis. Furthermore, local blood flow patterns of elder groups with snoring symptoms were more likely to be changed due to low-speed flow, increasing the possibility of vascular remodeling and thrombosis. Besides, increased snoring frequency hardly influenced the local disturbed flow. Therefore, older adults should receive medical treatment actively after stenting for high-amplitude snoring as soon as possible to avoid potential adverse events.
KW - carotid artery
KW - hemodynamics
KW - numerical study
KW - snoring
KW - stent
UR - https://www.scopus.com/pages/publications/85175641002
U2 - 10.37190/ABB-02207-2023-01
DO - 10.37190/ABB-02207-2023-01
M3 - 文章
C2 - 38314557
AN - SCOPUS:85175641002
SN - 1509-409X
VL - 25
SP - 35
EP - 45
JO - Acta of Bioengineering and Biomechanics
JF - Acta of Bioengineering and Biomechanics
IS - 1
ER -