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Enhancing SERS detection on a biocompatible metallic substrate for diabetes diagnosing

  • Zhiquan Cui
  • , Libin Lu
  • , Yingchun Guan*
  • , Seeram Ramakrishna
  • , Minghui Hong
  • *此作品的通讯作者
  • Beihang University
  • National University of Singapore

科研成果: 期刊稿件文章同行评审

摘要

A method to realize surface-enhanced Raman spectroscopy (SERS) at a titanium alloy substrate for glucose detection has been experimentally demonstrated. A silver-coated laser-induced periodic surface structure (LIPSS) was prepared via femtosecond laser micro-processing. The low detection limit of glucose is 10-7 mol/L and, a good linear relationship between the glucose concentration and Raman intensity is found in the range between 1 × 10-7 and 1 × 10-3 mol/L. Moreover, we investigate SERS detection for glucose sensing in human urine samples, while the results are in good agreement with clinical results. The Letter provides a facile method for producing a structure-controlled SERS substrate to realize glucose detection, which is promising for long-term in vivo diagnostics.

源语言英语
页(从-至)3801-3804
页数4
期刊Optics Letters
46
15
DOI
出版状态已出版 - 1 8月 2021

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