TY - GEN
T1 - Characterization of biomolecules using an aptamer-based graphene nanosensor
AU - Wang, Xuejun
AU - Hao, Zhuang
AU - Zhuang, Wenjun
AU - Lin, Qiao
N1 - Publisher Copyright:
© 2017 IEEE.
PY - 2017/2/23
Y1 - 2017/2/23
N2 - We present binding properties of biomolecules and their dependence on ionic strength and temperature using a microfluidic aptameric graphene field-effect transistor (FET) nanosensor. Aptamer-immobilized graphene is used to recognize target molecules, and the resulting changes in graphene conductance is measured to study the binding kinetics of biomolecules. Binding properties of aptamer-protein interactions at different ionic strength and temperature are investigated, yielding insight into the pharmacologic basis of biomolecular recognition.
AB - We present binding properties of biomolecules and their dependence on ionic strength and temperature using a microfluidic aptameric graphene field-effect transistor (FET) nanosensor. Aptamer-immobilized graphene is used to recognize target molecules, and the resulting changes in graphene conductance is measured to study the binding kinetics of biomolecules. Binding properties of aptamer-protein interactions at different ionic strength and temperature are investigated, yielding insight into the pharmacologic basis of biomolecular recognition.
UR - https://www.scopus.com/pages/publications/85015802137
U2 - 10.1109/MEMSYS.2017.7863469
DO - 10.1109/MEMSYS.2017.7863469
M3 - 会议稿件
AN - SCOPUS:85015802137
T3 - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
SP - 565
EP - 568
BT - 2017 IEEE 30th International Conference on Micro Electro Mechanical Systems, MEMS 2017
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 30th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2017
Y2 - 22 January 2017 through 26 January 2017
ER -