TY - GEN
T1 - Cell injection microrobot development and evaluation in microfluidic chip
AU - Zhou, Qiang
AU - Song, Bin
AU - Feng, Yanmin
AU - Feng, Lin
N1 - Publisher Copyright:
© 2018 IEEE.
PY - 2018/12
Y1 - 2018/12
N2 - We propose an innovative design of microrobot, which can achieve donor cell suction, delivery and injection in a mammalian oocyte on microfluidic chip. The microrobot body contains a hollow space that produces suction and ejection forces for injection of cell nuclei using a nozzle at the tip of the robot. Specifically, a controller changes the hollow volume by balancing the magnetic and elastic forces of the membrane, and along with motion of stages in the XY plane. A glass capillary attached at the tip of the robot contains the nozzle is able to absorb and inject cell nuclei. The microrobot provides three degrees of freedom and generates micronewton forces. We demonstrate the effectiveness of the proposed microrobot through an experiment of absorption and ejection of 20 \mu m particles from the nozzle using magnetic control in a microfluidic chip.
AB - We propose an innovative design of microrobot, which can achieve donor cell suction, delivery and injection in a mammalian oocyte on microfluidic chip. The microrobot body contains a hollow space that produces suction and ejection forces for injection of cell nuclei using a nozzle at the tip of the robot. Specifically, a controller changes the hollow volume by balancing the magnetic and elastic forces of the membrane, and along with motion of stages in the XY plane. A glass capillary attached at the tip of the robot contains the nozzle is able to absorb and inject cell nuclei. The microrobot provides three degrees of freedom and generates micronewton forces. We demonstrate the effectiveness of the proposed microrobot through an experiment of absorption and ejection of 20 \mu m particles from the nozzle using magnetic control in a microfluidic chip.
UR - https://www.scopus.com/pages/publications/85075011320
U2 - 10.1109/MHS.2018.8886994
DO - 10.1109/MHS.2018.8886994
M3 - 会议稿件
AN - SCOPUS:85075011320
T3 - MHS 2018 - 2018 29th International Symposium on Micro-NanoMechatronics and Human Science
BT - MHS 2018 - 2018 29th International Symposium on Micro-NanoMechatronics and Human Science
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 29th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2018
Y2 - 10 December 2018 through 12 December 2018
ER -