TY - GEN
T1 - Cell injection microrobot development and evaluation in microfluidic chip
AU - Feng, Lin
AU - Chen, DIxiao
AU - Zhou, Qiang
AU - Song, Bin
AU - Zhang, Wei
N1 - Publisher Copyright:
© 2019 IEEE.
PY - 2019/5
Y1 - 2019/5
N2 - We propose an innovative design of microrobot, which can achieve donor cell suction, delivery and injection in a mammalian oocyte on microfluidic chip. The microrobot body contains a hollow space that produces suction and ejection forces for injection of cell nuclei using a nozzle at the tip of the robot. Specifically, a controller changes the hollow volume by balancing the magnetic and elastic forces of the membrane, and along with motion of stages in the XY plane. A glass capillary attached at the tip of the robot contains the nozzle is able to absorb and inject cell nuclei. The microrobot provides three degrees of freedom and generates micronewton forces. We demonstrate the effectiveness of the proposed microrobot through an experiment of absorption and ejection of 20 μm particles from the nozzle using magnetic control in a microfluidic chip.
AB - We propose an innovative design of microrobot, which can achieve donor cell suction, delivery and injection in a mammalian oocyte on microfluidic chip. The microrobot body contains a hollow space that produces suction and ejection forces for injection of cell nuclei using a nozzle at the tip of the robot. Specifically, a controller changes the hollow volume by balancing the magnetic and elastic forces of the membrane, and along with motion of stages in the XY plane. A glass capillary attached at the tip of the robot contains the nozzle is able to absorb and inject cell nuclei. The microrobot provides three degrees of freedom and generates micronewton forces. We demonstrate the effectiveness of the proposed microrobot through an experiment of absorption and ejection of 20 μm particles from the nozzle using magnetic control in a microfluidic chip.
UR - https://www.scopus.com/pages/publications/85071463803
U2 - 10.1109/ICRA.2019.8793799
DO - 10.1109/ICRA.2019.8793799
M3 - 会议稿件
AN - SCOPUS:85071463803
T3 - Proceedings - IEEE International Conference on Robotics and Automation
SP - 4831
EP - 4836
BT - 2019 International Conference on Robotics and Automation, ICRA 2019
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2019 International Conference on Robotics and Automation, ICRA 2019
Y2 - 20 May 2019 through 24 May 2019
ER -