Arg-Gly-Asp (RGD) modified biomimetic polymeric materials

Xufeng Niu; Yuanliang Wang; Yanfeng Luo; Juan Xin; Yonggang Li

Arg-Gly-Asp (RGD) modified biomimetic polymeric materials

Xufeng Niu
, Yuanliang Wang^*
, Yanfeng Luo
, Juan Xin
, Yonggang Li

^*此作品的通讯作者

Chongqing University

科研成果: 期刊稿件 › 文章 › 同行评审

28 引用（Scopus）

摘要

The new generation of biomaterials focuses on the design of biomimetic polymeric materials that are capable of eliciting specific cellular responses and directing new tissue formation. Since Arg-Gly-Asp (RGD) sequences have been found to promote cell adhesion in 1984, numerous polymers have been functionalized with RGD peptides for tissue engineering applications. This review gave the advance in RGD modified biomimetic polymeric materials, focusing on the mechanism of RGD, the surface and bulk modification of polymer with RGD peptides and the evaluation in vitro and in vivo of the modified biomimetic materials.

源语言	英语
页（从-至）	571-576
页数	6
期刊	Journal of Materials Science and Technology
卷	21
期	4
出版状态	已出版 - 7月 2005
已对外发布	是

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abstract = "The new generation of biomaterials focuses on the design of biomimetic polymeric materials that are capable of eliciting specific cellular responses and directing new tissue formation. Since Arg-Gly-Asp (RGD) sequences have been found to promote cell adhesion in 1984, numerous polymers have been functionalized with RGD peptides for tissue engineering applications. This review gave the advance in RGD modified biomimetic polymeric materials, focusing on the mechanism of RGD, the surface and bulk modification of polymer with RGD peptides and the evaluation in vitro and in vivo of the modified biomimetic materials.",

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author = "Xufeng Niu and Yuanliang Wang and Yanfeng Luo and Juan Xin and Yonggang Li",

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AU - Niu, Xufeng

AU - Wang, Yuanliang

AU - Luo, Yanfeng

AU - Xin, Juan

AU - Li, Yonggang

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N2 - The new generation of biomaterials focuses on the design of biomimetic polymeric materials that are capable of eliciting specific cellular responses and directing new tissue formation. Since Arg-Gly-Asp (RGD) sequences have been found to promote cell adhesion in 1984, numerous polymers have been functionalized with RGD peptides for tissue engineering applications. This review gave the advance in RGD modified biomimetic polymeric materials, focusing on the mechanism of RGD, the surface and bulk modification of polymer with RGD peptides and the evaluation in vitro and in vivo of the modified biomimetic materials.

AB - The new generation of biomaterials focuses on the design of biomimetic polymeric materials that are capable of eliciting specific cellular responses and directing new tissue formation. Since Arg-Gly-Asp (RGD) sequences have been found to promote cell adhesion in 1984, numerous polymers have been functionalized with RGD peptides for tissue engineering applications. This review gave the advance in RGD modified biomimetic polymeric materials, focusing on the mechanism of RGD, the surface and bulk modification of polymer with RGD peptides and the evaluation in vitro and in vivo of the modified biomimetic materials.

KW - Arg-Gly-Asp (RGD)

KW - Biomimetic materials

KW - Polymer

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JO - Journal of Materials Science and Technology

JF - Journal of Materials Science and Technology

IS - 4

ER -

Arg-Gly-Asp (RGD) modified biomimetic polymeric materials

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