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Application of biodegradable implants in pediatric orthopedics: shifting from absorbable polymers to biodegradable metals

  • Yunan Lu
  • , Ting Zhang
  • , Kai Chen*
  • , Federico Canavese
  • , Chenyang Huang
  • , Hongtao Yang
  • , Jiahui Shi
  • , Wubing He*
  • , Yufeng Zheng*
  • , Shunyou Chen*
  • *此作品的通讯作者
  • Fujian Medical University
  • Peking University
  • University of Genoa
  • Beihang University
  • Fujian Provincial Clinical Medical Research Center for First Aid and Rehabilitation in Orthopedic Trauma (2020Y2014)
  • Key Clinical Specialty of Fujian Province and Fuzhou City (20220104)

科研成果: 期刊稿件文章同行评审

摘要

Over the past two decades, advances in pediatric orthopedics and closed reduction combined with percutaneous internal fixation techniques have led to significant growth in pediatric orthopedics surgery. Implants such as Kirschner-wires, cannulated screws and elastic stabilization intramedullary nails are commonly used in these procedures. However, traditional implants made of metal or inert materials are not absorbable, leading to complications that affect treatment outcomes. To address this issue, absorbable materials with excellent mechanical properties, good biocompatibility, and controlled degradation rates have been developed and applied in clinical practice. These materials include absorbable polymers and biodegradable metals. This article provides a comprehensive summary of these resorbable materials from a clinician's perspective. In addition, an in-depth discussion of the feasibility of their clinical applications and related research in pediatric orthopedics is included. We found that the applications of absorbable implants in pediatric orthopedics are shifting from absorbable polymers to biodegradable metals and emphasize that the functional characteristics of resorbable materials must be coordinated and complementary to the treatment in pediatric orthopedics.

源语言英语
页(从-至)189-214
页数26
期刊Bioactive Materials
50
DOI
出版状态已出版 - 8月 2025

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