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An analytic reflection method for time-domain fluorescence diffuse optical tomography based on a generalized pulse spectrum technique

  • Huiyuan He*
  • , Limin Zhang
  • , Feng Gao
  • , Zheng Ma
  • , Huijian Zhao
  • , Jingying Jiang
  • *此作品的通讯作者
  • Tianjin University

科研成果: 书/报告/会议事项章节会议稿件同行评审

摘要

An image reconstruction scheme for time-domain fluorescence diffuse optical tomography is proposed using a reflection-mode for a semi-infinite turbid geometry. The method is based on a generalized pulse spectrum technique that employs analytic expressions of the Laplace-transformed time-domain photon-diffusion model to construct a Born normalized inverse model, and a pair of real domain transform-factors to separate distributions of the fluorescent yield and lifetime. The methodology is validated with a specifically-developed fluorescent Monte-Carlo simulator or finite-element-based methods and its robustness to the background uncertainties is investigated.

源语言英语
主期刊名Multimodal Biomedical Imaging III
DOI
出版状态已出版 - 2008
已对外发布
活动Multimodal Biomedical Imaging III - San Jose, CA, 美国
期限: 19 1月 200821 1月 2008

出版系列

姓名Progress in Biomedical Optics and Imaging - Proceedings of SPIE
6850
ISSN(印刷版)1605-7422

会议

会议Multimodal Biomedical Imaging III
国家/地区美国
San Jose, CA
时期19/01/0821/01/08

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