Advances in magnetic particle imaging and perspectives on liver imaging

Magnetic particle imaging (MPI) is an emerging technique to visualize the spatial distribution of superparamagnetic iron oxide with high temporal–spatial resolution, high sensitivity, unlimited image depth, and true quantitative information. MPI is based on the nonlinear response of superparamagnetic iron oxide in an alternating magnetic field without tissue background noise. It is a promising imaging modality for various applications, including vascular imaging, cell tracking, tumor imaging, and catheter navigation. Many applications of liver imaging could be improved or created with MPI. In this review, we cover the principle and construction of MPI, we evaluate the features and advantages of MPI with relation to its own rationale and via comparison with other imaging modalities, and we review MPI liver imaging applications with a view toward assisting hepatic researchers in drawing inspiration.