Accurate Diagnosis of Prostate Cancer via Magnetic-Optical Dual-Modal Imaging Based on Dual-Target Probes

Wenjie Zhao; Yu An

doi:10.18416/IJMPI.2026.2604010

Accurate Diagnosis of Prostate Cancer via Magnetic-Optical Dual-Modal Imaging Based on Dual-Target Probes

Wenjie Zhao
, Yu An^*

^*此作品的通讯作者

医学科学与工程学院

Beihang University

科研成果: 期刊稿件 › 文章 › 同行评审

摘要

The heterogeneous expression of Prostate-Specific Membrane Antigen (PSMA), the primary Prostate Cancer (PCa) biomarker, contributes to significant underdiagnosis. Here, we developed a dual-targeted probe (MNP@FITC-WTN/Dye800CW-D7) against PSMA and Transferrin Receptor (TFR) to enable precise PCa diagnosis. Our probe exhibited enhanced tumor retention and a superior response rate over control groups.

源语言	英语
文章编号	2604010
期刊	International Journal on Magnetic Particle Imaging
卷	12
期	1
DOI	https://doi.org/10.18416/IJMPI.2026.2604010
出版状态	已出版 - 2026

联合国可持续发展目标

此成果有助于实现下列可持续发展目标：

可持续发展目标 3 良好健康与福祉

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10.18416/IJMPI.2026.2604010

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title = "Accurate Diagnosis of Prostate Cancer via Magnetic-Optical Dual-Modal Imaging Based on Dual-Target Probes",

abstract = "The heterogeneous expression of Prostate-Specific Membrane Antigen (PSMA), the primary Prostate Cancer (PCa) biomarker, contributes to significant underdiagnosis. Here, we developed a dual-targeted probe (MNP@FITC-WTN/Dye800CW-D7) against PSMA and Transferrin Receptor (TFR) to enable precise PCa diagnosis. Our probe exhibited enhanced tumor retention and a superior response rate over control groups.",

author = "Wenjie Zhao and Yu An",

note = "Publisher Copyright: {\textcopyright} 2026 Zhao et al.",

year = "2026",

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AU - Zhao, Wenjie

AU - An, Yu

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AB - The heterogeneous expression of Prostate-Specific Membrane Antigen (PSMA), the primary Prostate Cancer (PCa) biomarker, contributes to significant underdiagnosis. Here, we developed a dual-targeted probe (MNP@FITC-WTN/Dye800CW-D7) against PSMA and Transferrin Receptor (TFR) to enable precise PCa diagnosis. Our probe exhibited enhanced tumor retention and a superior response rate over control groups.

UR - https://www.scopus.com/pages/publications/105038637856

U2 - 10.18416/IJMPI.2026.2604010

DO - 10.18416/IJMPI.2026.2604010

M3 - 文章

AN - SCOPUS:105038637856

SN - 2365-9033

VL - 12

JO - International Journal on Magnetic Particle Imaging

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IS - 1

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Accurate Diagnosis of Prostate Cancer via Magnetic-Optical Dual-Modal Imaging Based on Dual-Target Probes

摘要

联合国可持续发展目标

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