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A flexible graphene aptameric nanosensor for detection of TNF-¢

  • Zhuang Hao*
  • , Yibo Zhu
  • , Yijun Li
  • , Xuejun Wang
  • , Xuezeng Zhao
  • , Qiao Lin
  • *此作品的通讯作者
  • Columbia University
  • Harbin Institute of Technology

科研成果: 书/报告/会议事项章节会议稿件同行评审

摘要

We present a flexible graphene aptameric nanosensor, which can work properly under different bending radii, for rapid, direct, highly sensitive and label-free detection of TNF-α in physiologically relevant levels. The nanosensor is configured as an electrolyte-gated graphene field-effect transistor (GFET) and fabricated on a SiO2 covered polyethylene naphthalate (PEN) substrate. The detection is enabled by the affinity binding between TNF-α and graphene surface immobilized aptamer VR11. We characterized our flexible nanosensor with multiple TNF-α concentrations ranging from 5 nM to 500 nM under different bending radii.

源语言英语
主期刊名21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
出版商Chemical and Biological Microsystems Society
483-484
页数2
ISBN(电子版)9780692941836
出版状态已出版 - 2020
已对外发布
活动21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 - Savannah, 美国
期限: 22 10月 201726 10月 2017

出版系列

姓名21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017

会议

会议21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
国家/地区美国
Savannah
时期22/10/1726/10/17

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