用于颈动脉风险评估的生物力学参数研究综述

Carotid is in a high risk of atherosclerosis due to its special geometric features and complex flow characteristics. Various biomechanical parameters are practical tools for carotid risk assessment. It has been widely accepted that oscillatory low shear environment promotes plaque formation. Based on this, more and more biomechanical indexes have been proposed, such as time-average wall shear stress, oscillatory shear index, relative residence time and so on. In this paper, multiple biomechanical parameters were introduced from the perspectives of shear stress and its temporal and spatial variation, turbulence, platelet transport and activation, stress concentration in vascular wall, etc. The development trend of biomechanical parameters related to carotid artery risk assessment was also analyzed, so as to provide the theoretical basis for more comprehensive and rapid carotid risk assessment.