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Viscoelastic properties of phagocytes in arteriosclerotic origin

  • Sichuan University of Science & Engineering

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

A micropipette aspiration technique was adopted to investigate the viscoelastic properties of phagocytes of arteriosclerotic origin. A standard linear solid model was employed to fit the experimental data and three viscoelastic coefficients were used to compare the mechanical properties of the phagocytes in different phases during arteriosclerostic development. The experimental results indicated that prior to the formation of arteriosclerosis, the mobility and deformability of the marcopahges matured from monocytes decreased, and their rigidity increased. At the initial stage of arteriosclerosis formation, the mobility and deformability of the foam-cells further decreased. This finding may have important implication in the research field of arteriosclerosis.

Original languageEnglish
Title of host publicationAdvanced Research on Mechanics, Manufacturing Engineering and Applied Technology II
PublisherTrans Tech Publications
Pages321-325
Number of pages5
ISBN (Print)9783038350958
DOIs
StatePublished - 2014
Event2nd International Conference on Applied Mechanics and Manufacturing System, AMMS 2014 - Zhengzhou, China
Duration: 26 Apr 201427 Apr 2014

Publication series

NameApplied Mechanics and Materials
Volume540
ISSN (Print)1660-9336
ISSN (Electronic)1662-7482

Conference

Conference2nd International Conference on Applied Mechanics and Manufacturing System, AMMS 2014
Country/TerritoryChina
CityZhengzhou
Period26/04/1427/04/14

Keywords

  • Arteriosclerosis
  • Micropipette aspiration
  • Phagocyte
  • Viscoelasticity

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