Two-photon endomicroscopy with microsphere-spliced double-cladding antiresonant fiber for resolution enhancement

Conghao Wang; Huilan Liu; Haodong Cui; Jianrui Ma; Yijun Li; Jingquan Tian; Chaoyong Jin; Yanchuan Chen; Yuqian Gao; Qiang Fu; Yanhui Hu; Dakun Wu; Fei Yu; Runlong Wu; Aimin Wang; Lishuang Feng

doi:10.1364/OE.461325

Two-photon endomicroscopy with microsphere-spliced double-cladding antiresonant fiber for resolution enhancement

Conghao Wang
, Huilan Liu
, Haodong Cui
, Jianrui Ma
, Yijun Li
, Jingquan Tian
, Chaoyong Jin
, Yanchuan Chen
, Yuqian Gao
, Qiang Fu
, Yanhui Hu
, Dakun Wu
, Fei Yu
, Runlong Wu
, Aimin Wang
, Lishuang Feng^*

^*Corresponding author for this work

School of Instrumentation and Optoelectronic Engineering

Beihang University
Ltd
LUSTER LightTech Co. Ltd.
University of Chinese Academy of Sciences
CAS - Shanghai Institute of Optics and Fine Mechanics
Peking University

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

We demonstrate a miniature fiber-optic two two-photon endomicroscopy with microsphere-spliced double-cladding antiresonant fiber for resolution enhancement. An easy-tooperate process for fixing microsphere permanently in an antiresonant fiber core, by arc discharge, is proposed. The flexible fiber-optic probe is integrated with a parameter of 5.8mm× 49.1mm (outer diameter × rigid length); the field of view is 210 μm, the resolution is 1.3 μm, and the frame rate is 0.7 fps. The imaging ability is verified using ex-vivo mouse kidney, heart, stomach, tail tendon, and in-vivo brain neural imaging.

Original language	English
Pages (from-to)	26090-26101
Number of pages	12
Journal	Optics Express
Volume	30
Issue number	15
DOIs	https://doi.org/10.1364/OE.461325
State	Published - 18 Jul 2022

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title = "Two-photon endomicroscopy with microsphere-spliced double-cladding antiresonant fiber for resolution enhancement",

abstract = "We demonstrate a miniature fiber-optic two two-photon endomicroscopy with microsphere-spliced double-cladding antiresonant fiber for resolution enhancement. An easy-tooperate process for fixing microsphere permanently in an antiresonant fiber core, by arc discharge, is proposed. The flexible fiber-optic probe is integrated with a parameter of 5.8mm{\texttimes} 49.1mm (outer diameter {\texttimes} rigid length); the field of view is 210 μm, the resolution is 1.3 μm, and the frame rate is 0.7 fps. The imaging ability is verified using ex-vivo mouse kidney, heart, stomach, tail tendon, and in-vivo brain neural imaging.",

author = "Conghao Wang and Huilan Liu and Haodong Cui and Jianrui Ma and Yijun Li and Jingquan Tian and Chaoyong Jin and Yanchuan Chen and Yuqian Gao and Qiang Fu and Yanhui Hu and Dakun Wu and Fei Yu and Runlong Wu and Aimin Wang and Lishuang Feng",

note = "Publisher Copyright: {\textcopyright} 2022 Optica Publishing Group.",

year = "2022",

month = jul,

day = "18",

doi = "10.1364/OE.461325",

language = "英语",

volume = "30",

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TY - JOUR

T1 - Two-photon endomicroscopy with microsphere-spliced double-cladding antiresonant fiber for resolution enhancement

AU - Wang, Conghao

AU - Liu, Huilan

AU - Cui, Haodong

AU - Ma, Jianrui

AU - Li, Yijun

AU - Tian, Jingquan

AU - Jin, Chaoyong

AU - Chen, Yanchuan

AU - Gao, Yuqian

AU - Fu, Qiang

AU - Hu, Yanhui

AU - Wu, Dakun

AU - Yu, Fei

AU - Wu, Runlong

AU - Wang, Aimin

AU - Feng, Lishuang

PY - 2022/7/18

Y1 - 2022/7/18

N2 - We demonstrate a miniature fiber-optic two two-photon endomicroscopy with microsphere-spliced double-cladding antiresonant fiber for resolution enhancement. An easy-tooperate process for fixing microsphere permanently in an antiresonant fiber core, by arc discharge, is proposed. The flexible fiber-optic probe is integrated with a parameter of 5.8mm× 49.1mm (outer diameter × rigid length); the field of view is 210 μm, the resolution is 1.3 μm, and the frame rate is 0.7 fps. The imaging ability is verified using ex-vivo mouse kidney, heart, stomach, tail tendon, and in-vivo brain neural imaging.

AB - We demonstrate a miniature fiber-optic two two-photon endomicroscopy with microsphere-spliced double-cladding antiresonant fiber for resolution enhancement. An easy-tooperate process for fixing microsphere permanently in an antiresonant fiber core, by arc discharge, is proposed. The flexible fiber-optic probe is integrated with a parameter of 5.8mm× 49.1mm (outer diameter × rigid length); the field of view is 210 μm, the resolution is 1.3 μm, and the frame rate is 0.7 fps. The imaging ability is verified using ex-vivo mouse kidney, heart, stomach, tail tendon, and in-vivo brain neural imaging.

UR - https://www.scopus.com/pages/publications/85138770918

U2 - 10.1364/OE.461325

DO - 10.1364/OE.461325

M3 - 文章

C2 - 36236806

AN - SCOPUS:85138770918

SN - 1094-4087

VL - 30

SP - 26090

EP - 26101

JO - Optics Express

JF - Optics Express

IS - 15

ER -

Two-photon endomicroscopy with microsphere-spliced double-cladding antiresonant fiber for resolution enhancement

Abstract

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