Temperature distribution and damage of thrombus induced by pulsed laser

In the process of laser thermal ablation, real-time observation of temperature distribution and damage is helpful to guide the laser thrombolysis process. However, in actual operation, it is difficult to predict the effect of laser parameters on the thermal effect of thrombus. It is of great significance to use finite element simulation method to study the influence of different laser parameters, such as power, time, spot size, pulse width, pulse interval, absorption coefficient, and laser mode on the surface temperature and damage of thrombus. The influence of power and time on temperature and damage in the simulation are verified by experiment, and the trend of experimental variation is consistent with the simulation results. The simulation results will provide theoretical guidance for selecting the optimal laser parameters in subsequent experiments.