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Study on nano-hydroxyapatite/silk fibroin biomedical composite under biomimetic mineralization

  • Hainan University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

A novel nano-Hydroxyapatite/Silk Fibroin (n-HA/SF) composite was prepared by biomimetic mineralization method. It was revealed that the inorganic phase in the composite was n-HA with low crystallinity. The composite exhibited a higher compressive strength, which was closely related to the perfect incorporation of SF macromolecules into the composite. The chemical interactions occurring between phase and the organic matrix were thought to improve the interfacial bonding and thus resulted in the enhanced mechanical strength. Finally, MTT and SEM results showed that this synthesized composite was nontoxic and no allergic, and possessed excellent compatibility. Therefore, the n-HA/SF composite prepared in this paper was prospective to be used as a new biomaterial for bone repair or substitute.

Original languageEnglish
Title of host publication6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech
Pages1218-1221
Number of pages4
DOIs
StatePublished - 2010
Event6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech - Singapore, Singapore
Duration: 1 Aug 20106 Aug 2010

Publication series

NameIFMBE Proceedings
Volume31 IFMBE
ISSN (Print)1680-0737

Conference

Conference6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech
Country/TerritorySingapore
CitySingapore
Period1/08/106/08/10

Keywords

  • Nano-hydroxyapatite
  • biomimetic mineralization
  • composite
  • silk fibroin

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