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Study delay and dispersion effects in dynamic susceptibility contrast MRI based on local density random walk distribution

  • Xingfeng Li
  • , Jie Tian*
  • , Xiaoxiang Wang
  • , Jianping Dai
  • , Lin Ai
  • *Corresponding author for this work
  • CAS - Institute of Automation
  • Capital Medical University

Research output: Contribution to journal › Conference article › peer-review

Abstract

The aim of this study was to assess the validation of using the local density random walk (LDRW) function to correct the delayed and dispersed arterial input function (AIF) data derived from dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI).Instead of using the gamma-variate function to smooth and extrapolate the AIF curves, we suggested a method which was based on diffusion with drift approach. Forty-seven AIF curves from ten patients were segmented to test the effectiveness of the proposed method. The results of the comparisons with the gamma-variate function showed that the LDRW distribution function may provide a new means for more accurate correction of AIF curves.

Original languageEnglish
Pages (from-to)550-557
Number of pages8
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume5369
DOIs
StatePublished - 2004
Externally publishedYes
EventMedical Imaging 2004: Physiology, Function, and Structure from Medical Images - San Diego, CA, United States
Duration: 15 Feb 2004 → 17 Feb 2004

Keywords

  • Arterial input function
  • Cerebral blood flow
  • DSC-MRI
  • Local density random walk function

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