Abstract
Cancer cells adopt metabolic pathways that differ from their normal counterparts by reprogramming metabolism of essential biomolecules to fuel rapid growth. Cancer metabolism is intrinsically heterogeneous and dynamic at the cellular level. This highlights an urgent need of developing novel imaging methods to study single cancer cell metabolism in situ. With the capability of high detection sensitivity, high molecular specificity, and high spatiotemporal resolution, stimulated Raman scattering microscopy integrated with Raman tagging offers a novel platform to discover hidden molecular signatures of cancer metabolism and further opens new avenue to precision diagnosis and treatment of human cancers.
| Original language | English |
|---|---|
| Title of host publication | Stimulated Raman Scattering Microscopy |
| Subtitle of host publication | Techniques and Applications |
| Publisher | Elsevier |
| Pages | 463-473 |
| Number of pages | 11 |
| ISBN (Electronic) | 9780323851589 |
| ISBN (Print) | 9780323903370 |
| DOIs | |
| State | Published - 1 Jan 2021 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Cancer diagnosis
- Cancer metabolism
- Cancer treatment
- Precision medicine
- Stimulated raman scattering
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