Piezoelectric ultrasonic focusing system for jetting biological microarrays

A piezoelectric ultrasonic focusing system is developed for microjetting biological microarrays. Compared with other microjetting methods used for biological microarrays, the ultrasonic jetting has the advantages of mild process and clog-free. In order to increase microarray's alignment and regularity, and reduce the diameters of jetted dots and the volume of the expensive agents, a downward and isolated layout is adopted. Experiments showed that the jetting microarrays with composed of well aligned regular dots and with the dot diameters below ø 100 μm can be realized.