Optical super-resolution imaging study based on controlling liquid-immersed microsphere

  • Kai Meng
  • , Shilin Gao
  • , Yunlin Zhang
  • , Lei Yang
  • , Tao Chen*
  • , Zhan Yang
  • , Huicong Liu
  • , Lining Sun
  • *Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Super-resolution images beyond classic diffraction limit can be generated by microspheres with appropriate refractive index. This paper presented a method of controlling liquid-immersed microsphere for achieving images with a resolution beyond the diffraction limit. The microsphere was attached to the probe using optical glue. The optical simulation has been performed to demonstrate the influence of probe on super-resolution image. To improve imaging quality, the microsphere was immersed in liquid medium. The probe was fixed in a translation stage which was regarded as a robotic manipulator with four degrees of freedoms (DOF). By scanning the submerged microsphere over the sample surface at the speed of 5x10 -6 m/s, the super-resolution image of large continuous region was obtained. This work has developed a new alternative for real-Time optical super-resolution imaging, and can be practically applied in multifarious fields of scientific research.

Original languageEnglish
Title of host publicationNEMS 2018 - 13th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages538-542
Number of pages5
ISBN (Electronic)9781538652732
DOIs
StatePublished - 3 Dec 2018
Externally publishedYes
Event13th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2018 - Singapore, Singapore
Duration: 22 Apr 201826 Apr 2018

Publication series

NameNEMS 2018 - 13th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems

Conference

Conference13th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2018
Country/TerritorySingapore
CitySingapore
Period22/04/1826/04/18

Keywords

  • Micro-manipulation
  • Microsphere
  • Robotic manipulator
  • Super-resolution

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