TY - GEN
T1 - Online monitoring and flow regime identification of fluidised bed drying and granulation processes
AU - Wang, Haigang
AU - Yang, Wuqiang
AU - Proctor, Ian
AU - Taylor, Julian
AU - Marr, Alex
AU - Page, Trevor
PY - 2009
Y1 - 2009
N2 - Fluidised beds are widely used in the pharmaceutical industry for granulation, drying and coating. The product quality strongly depends on the operation parameters and process conditions, e.g. inlet airflow rate, temperature and spraying flow rate. For granulation and drying processes, the flow conditions can change dramatically due to different moisture level, because of the change in physical characteristics of particles, including viscosity, density and diameter. Also, the flow regime of a fluidised bed would change with the diameter and density of particles. Due to high moisture content, particles could agglomerate and stick up to the wall and distributor plate, resulting in a fault process. Therefore, it is necessary to monitor a drying or granulation process, identify their flow regime and control the processes according to the particle properties. This paper describes an application of electrical capacitance tomography (ECT) to monitor the process conditions and for diagnosis of fault with a semi-industrial scale pharmaceutical fluidised bed. Preliminary test results with granulation and drying processes are given. Future work on fluidised bed control based on the information provided by ECT will be discussed.
AB - Fluidised beds are widely used in the pharmaceutical industry for granulation, drying and coating. The product quality strongly depends on the operation parameters and process conditions, e.g. inlet airflow rate, temperature and spraying flow rate. For granulation and drying processes, the flow conditions can change dramatically due to different moisture level, because of the change in physical characteristics of particles, including viscosity, density and diameter. Also, the flow regime of a fluidised bed would change with the diameter and density of particles. Due to high moisture content, particles could agglomerate and stick up to the wall and distributor plate, resulting in a fault process. Therefore, it is necessary to monitor a drying or granulation process, identify their flow regime and control the processes according to the particle properties. This paper describes an application of electrical capacitance tomography (ECT) to monitor the process conditions and for diagnosis of fault with a semi-industrial scale pharmaceutical fluidised bed. Preliminary test results with granulation and drying processes are given. Future work on fluidised bed control based on the information provided by ECT will be discussed.
KW - Drying
KW - Electrical capacitance tomography
KW - Fluidised bed
KW - Granulation
UR - https://www.scopus.com/pages/publications/70349687593
U2 - 10.1109/IST.2009.5071643
DO - 10.1109/IST.2009.5071643
M3 - 会议稿件
AN - SCOPUS:70349687593
SN - 9781424434831
T3 - 2009 IEEE International Workshop on Imaging Systems and Techniques, IST 2009 - Proceedings
SP - 253
EP - 257
BT - 2009 IEEE International Workshop on Imaging Systems and Techniques, IST 2009 - Proceedings
T2 - 2009 IEEE International Workshop on Imaging Systems and Techniques, IST 2009
Y2 - 11 May 2009 through 12 May 2009
ER -