Numerical simulation of low density lipoprotein (LDL) transport in arterial stenoses

  • Xiaoyan Deng*
  • , Nasser Fatouraee
  • , Robert Guidoin
  • *Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The transport of atherogenic lipids (LDL) in an arterial stenosis with a semi-permeable wall was simulated numerically. The numerical analysis predicted lipid accumulation at the blood/arterial wall interface, with the highest concentration occurring at the flow separation point right distal to the summit of the stenosis. The analysis also predicted that the larger the Schmidt number (i.e., the larger the lipids), the higher the peak value of the luminal surface lipid concentration. The fluid layer with highly concentrated lipids in the area of flow separation point may be responsible for the formation and development of the arterial stenosis.

Original languageEnglish
Title of host publicationProceedings of the Second IASTED International Conference on Biomechanics
EditorsM.H. Hamza
Pages94-96
Number of pages3
StatePublished - 2004
Externally publishedYes
EventProceedings of the Second IASTED International Conference on Biomechanics - Honolulu, HI, United States
Duration: 23 Aug 200425 Aug 2004

Publication series

NameProceedings of the Second IASTED International Conference on Biomechanics

Conference

ConferenceProceedings of the Second IASTED International Conference on Biomechanics
Country/TerritoryUnited States
CityHonolulu, HI
Period23/08/0425/08/04

Keywords

  • Atherosclorosis
  • Hemodynamics
  • Low density lipoprotein
  • Mass transport
  • Water permeability

Fingerprint

Dive into the research topics of 'Numerical simulation of low density lipoprotein (LDL) transport in arterial stenoses'. Together they form a unique fingerprint.

Cite this