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Multi-objective particle swarm optimization biclustering of microarray data

  • Junwan Liu*
  • , Zhoujun Li
  • , Feifei Liu
  • , Yiming Chen
  • *Corresponding author for this work
  • National University of Deference Technology
  • Central South University of Forestry & Technology

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

With the advent of the DNA microarray technology, it is now possible to study the transcriptional response of a complete genome to different experimental conditions. Biclustering is a very useful data mining technique for analysis of those gene expression data. During biclustering several objectives in conflict with each other have to be optimized simultaneously, so multi-objective modeling is suitable for solving biclustering problem. This paper proposes a novel multi-objective particle swarm optimization biclustering (MOPSOB) algorithm to mine coherent patterns from microarray data. Experimental results on real datasets show that our approach can effectively find significant biclusters of high quality.

Original languageEnglish
Title of host publicationProceedings - IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2008
Pages363-366
Number of pages4
DOIs
StatePublished - 2008
Externally publishedYes
Event2008 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2008 - Philadelphia, PA, United States
Duration: 3 Nov 20085 Nov 2008

Publication series

NameProceedings - IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2008

Conference

Conference2008 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2008
Country/TerritoryUnited States
CityPhiladelphia, PA
Period3/11/085/11/08

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