Low noise amplifier with active feedback structure for implantable neural recording

Hongge Li; Wei Zhao; Hui Shen; Youguang Zhang

doi:10.1587/elex.10.20130312

Low noise amplifier with active feedback structure for implantable neural recording

School of Electronic and Information Engineering

Beihang University

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

A novel low-power, low-noise amplifier is described for biomedical and bioengineering brain neural recording applications. The bioamplifier achieves the best power-size tradeoff compared to the previous design. By means of a new active feedback configuration, the DC offset is rejected without the large capacitors. An active differentiator with an amplifier in the feedback path places a high-pass cutting frequency in the transfer function. The midband gain consists of the passive components, and is insensitive to the mismatch of process. The bioamplifier has been implemented in the 0.35-μm 2P4M CMOS process and occupies 0.052mm² of die area. The current consumption of amplifier is 2 μA at ±1.5V supply. The bioamplifier achieves a midband gain of 42 dB and a -3 dB bandwidth from 13 Hz to 10.5 kHz.The input-referred noise is 5.7 μV_rms corresponding to an NEF of 3.1.

Original language	English
Article number	20130312
Journal	IEICE Electronics Express
Volume	10
Issue number	19
DOIs	https://doi.org/10.1587/elex.10.20130312
State	Published - 2013

Keywords

Active feedback
Bioamplifier
Dc-offset
Low noise

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10.1587/elex.10.20130312

Cite this

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title = "Low noise amplifier with active feedback structure for implantable neural recording",

abstract = "A novel low-power, low-noise amplifier is described for biomedical and bioengineering brain neural recording applications. The bioamplifier achieves the best power-size tradeoff compared to the previous design. By means of a new active feedback configuration, the DC offset is rejected without the large capacitors. An active differentiator with an amplifier in the feedback path places a high-pass cutting frequency in the transfer function. The midband gain consists of the passive components, and is insensitive to the mismatch of process. The bioamplifier has been implemented in the 0.35-μm 2P4M CMOS process and occupies 0.052mm2 of die area. The current consumption of amplifier is 2 μA at ±1.5V supply. The bioamplifier achieves a midband gain of 42 dB and a -3 dB bandwidth from 13 Hz to 10.5 kHz.The input-referred noise is 5.7 μVrms corresponding to an NEF of 3.1.",

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author = "Hongge Li and Wei Zhao and Hui Shen and Youguang Zhang",

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AU - Li, Hongge

AU - Zhao, Wei

AU - Shen, Hui

AU - Zhang, Youguang

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N2 - A novel low-power, low-noise amplifier is described for biomedical and bioengineering brain neural recording applications. The bioamplifier achieves the best power-size tradeoff compared to the previous design. By means of a new active feedback configuration, the DC offset is rejected without the large capacitors. An active differentiator with an amplifier in the feedback path places a high-pass cutting frequency in the transfer function. The midband gain consists of the passive components, and is insensitive to the mismatch of process. The bioamplifier has been implemented in the 0.35-μm 2P4M CMOS process and occupies 0.052mm2 of die area. The current consumption of amplifier is 2 μA at ±1.5V supply. The bioamplifier achieves a midband gain of 42 dB and a -3 dB bandwidth from 13 Hz to 10.5 kHz.The input-referred noise is 5.7 μVrms corresponding to an NEF of 3.1.

AB - A novel low-power, low-noise amplifier is described for biomedical and bioengineering brain neural recording applications. The bioamplifier achieves the best power-size tradeoff compared to the previous design. By means of a new active feedback configuration, the DC offset is rejected without the large capacitors. An active differentiator with an amplifier in the feedback path places a high-pass cutting frequency in the transfer function. The midband gain consists of the passive components, and is insensitive to the mismatch of process. The bioamplifier has been implemented in the 0.35-μm 2P4M CMOS process and occupies 0.052mm2 of die area. The current consumption of amplifier is 2 μA at ±1.5V supply. The bioamplifier achieves a midband gain of 42 dB and a -3 dB bandwidth from 13 Hz to 10.5 kHz.The input-referred noise is 5.7 μVrms corresponding to an NEF of 3.1.

KW - Active feedback

KW - Bioamplifier

KW - Dc-offset

KW - Low noise

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DO - 10.1587/elex.10.20130312

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Low noise amplifier with active feedback structure for implantable neural recording

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