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Lensed fiber-optic scanning two-photon endomicroscopic imaging

  • Beihang University
  • Key Laboratory of Precision Opto-Mechatronics Technology (Ministry of Education)
  • Peking University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

In recent years, two-photon endomicroscopy has developed as a promising label-free optical biopsy technique for diagnosing gastrointestinal tumors. In this study, we optimize the imaging resolution of the lensed fiber-optic scanning two-photon endomicroscopic imaging scheme. By fabricating a lensed fiber for fiber-optic scanning two-photon endomicroscopy, a lateral resolution of 2.1 μm and a field of view of 600 μm in two-photon endomicroscopic imaging is achieved. Furthermore, the objective-lens-free imaging capability is also validated using gastric wall tissue sections.

Original languageEnglish
Title of host publicationSecond Conference on Biomedical Photonics and Cross-Fusion, BPC 2023
EditorsZhenxi Zhang, Junle Qu, Buhong Li
PublisherSPIE
ISBN (Electronic)9781510667549
DOIs
StatePublished - 2023
Event2nd Conference on Biomedical Photonics and Cross-Fusion, BPC 2023 - Shanghai, China
Duration: 8 Jun 202310 Jun 2023

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume12753
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Conference

Conference2nd Conference on Biomedical Photonics and Cross-Fusion, BPC 2023
Country/TerritoryChina
CityShanghai
Period8/06/2310/06/23

Keywords

  • Lensed fiber
  • endomicroscopic imaging
  • fiber-optic scanning
  • two-photon imaging

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