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Label-free Detection of In Vivo-like Cells with a Terahertz Metamaterial Sensor Chip

  • Lulu Han
  • , Kanglong Chen
  • , Cunjun Ruan*
  • , Qinggang Ge
  • , Jun Yang
  • *Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

In this paper, we propose a biosensor chip composed of metamaterials and a cavity for label-free measurements of in vivo-like cells. The ~50 μm thick cavity effectively reduces water absorption of terahertz waves, maintains an aqueous environment, and ensures consistent sample thickness. The biosensor chip effectively distinguishes between different densities of Neurons, demonstrating a resonance frequency difference of ~50 GHz. This study introduces a highly sensitive terahertz detection method for cells in an in vivo-like condition, offering a new, rapid, cost-effective, and highly sensitive approach to biosensing.

Original languageEnglish
Title of host publication50th International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2025
PublisherIEEE Computer Society
ISBN (Electronic)9798350378832
DOIs
StatePublished - 2025
Event50th International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2025 - Espoo, Finland
Duration: 17 Aug 202522 Aug 2025

Publication series

NameInternational Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz
ISSN (Print)2162-2027
ISSN (Electronic)2162-2035

Conference

Conference50th International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2025
Country/TerritoryFinland
CityEspoo
Period17/08/2522/08/25

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