Interaction of HIV infection with nervous tissue may play a crucial role in the development of AIDS

  • G. Parisi*
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

In this note, we first review some of the immunopathogenic mechanisms of HIV infection and discuss the possible role of the idiotypic network in producing immunodeficiency; we then propose that the interaction of HIV with the nervous system is such as to generate signals which are misinterpreted by the nervous system: the feedback reaction of the nervous system may play a crucial role in the development of AIDS. We conclude by studying a very simple model for the dynamics of AIDS.

Original languageEnglish
Pages (from-to)467-476
Number of pages10
JournalAnnales de l'Institut Pasteur Virology
Volume139
DOIs
StatePublished - 1988
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • AIDS
  • HIV
  • Hypothesis
  • Hypothèse
  • Lymphocyte
  • Lymphocyte
  • Nervous system
  • SIDA
  • Système nerveux
  • VIH

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