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Influence of cholesterol on non-invasive blood glucose sensing studied with NIR spectroscopy

  • Jingying Jiang*
  • , Lingling Zhang
  • , Qiliang Gong
  • , Kexin Xu
  • *Corresponding author for this work
  • Tianjin University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

There is a growing body of studies suggesting that NIR spectroscopy is feasible to be used to non-invasive blood glucose sensing. However, previous results reported that blood components are very complicated and in which glucose concentration is relatively low. This feature limited the practical application of NIR spectroscopy to in vivo blood glucose detection. This talk aims to elucidate how the cholesterol influences blood glucose sensing. Spectroscopic measurements show that cholesterol appears the similar absorbance peaks to those of glucose within NIR range. Furthermore, PLS modelling results demonstrate that the measurement concentrations of glucose are on the high side while containing cholesterol. For example, when the cholesterol concentration is 200mg/dl, the measurement result of glucose with near-infrared spectroscopy will increase 7.961882mg/dl comparing to cholesterol-free glucose solution. Therefore, it is necessary to take steps to reduce cholesterol's effects.

Original languageEnglish
Title of host publicationDynamics and Fluctuations in Biomedical Photonics VIII
DOIs
StatePublished - 2011
Externally publishedYes
EventDynamics and Fluctuations in Biomedical Photonics VIII - San Francisco, CA, United States
Duration: 22 Jan 201124 Jan 2011

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7898
ISSN (Print)1605-7422

Conference

ConferenceDynamics and Fluctuations in Biomedical Photonics VIII
Country/TerritoryUnited States
CitySan Francisco, CA
Period22/01/1124/01/11

Keywords

  • Cholesterol
  • Non-invasive blood glucose sensing
  • Optical properties
  • Predicting precision

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