In vitro degradation of chitosan under mechanical load

  • Ping Li
  • , Xiaoliang Feng
  • , Lu Jia
  • , Jingwen Li
  • , Chunqiu Zhang
  • , Yubo Fan*
  • *Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The effect of mechanical load on the degradation of chitosan foam was investigated in phosphate buffered saline (PBS) at 37 °C and pH 7.4 with a specially designed experimental device supplying rolling load. Degradation of chitosan scaffold under load or no load lasted for 8 days. Changes in increase of mass loss and decrease of water absorption happened more significantly under rolling load. It is indicated that the mechanical load can accelerate the degradation velocity of chitosan scaffold.

Original languageEnglish
Title of host publicationWorld Congress on Medical Physics and Biomedical Engineering
Subtitle of host publicationBiomaterials, Cellular and Tissue Engineering, Artificial Organs
PublisherSpringer Verlag
Pages75-76
Number of pages2
Edition10
ISBN (Print)9783642038990
DOIs
StatePublished - 2009
EventWorld Congress on Medical Physics and Biomedical Engineering: Biomaterials, Cellular and Tissue Engineering, Artificial Organs - Munich, Germany
Duration: 7 Sep 200912 Sep 2009

Publication series

NameIFMBE Proceedings
Number10
Volume25
ISSN (Print)1680-0737

Conference

ConferenceWorld Congress on Medical Physics and Biomedical Engineering: Biomaterials, Cellular and Tissue Engineering, Artificial Organs
Country/TerritoryGermany
CityMunich
Period7/09/0912/09/09

Keywords

  • Chitosan scaffold
  • Degradation
  • Rolling load

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