In vitro cell stretching devices and their applications: From cardiomyogenic differentiation to tissue engineering

Jiangtao Zhao; Fanzhe Meng; Jiayi Qian; Yan Huang; Yubo Fan

doi:10.1016/j.medntd.2023.100220

In vitro cell stretching devices and their applications: From cardiomyogenic differentiation to tissue engineering

Jiangtao Zhao
, Fanzhe Meng
, Jiayi Qian
, Yan Huang^*
, Yubo Fan^*

^*Corresponding author for this work

Beihang University

Research output: Contribution to journal › Review article › peer-review

16 Scopus citations

Abstract

Mechanical stretch plays an important role in the control of cardiomyocyte behavior, as well as in the study of the mechanisms of cardiovascular function and pathology. The complexity involved in biological systems in vivo has created a need for better in vitro techniques, thus a variety of cell stretching devices have been developed for a deeper understanding of cellular responses to strain. In this review, we introduce the design, functionality, and characteristics of multiple types of cell stretching devices from two and three dimensions, then discuss the research progress of promoting cardiomyogenic differentiation of stem cells by external stretching and its application in cardiac tissue engineering.

Original language	English
Article number	100220
Journal	Medicine in Novel Technology and Devices
Volume	18
DOIs	https://doi.org/10.1016/j.medntd.2023.100220
State	Published - Jun 2023

Keywords

Cardiomyogenic differentiation
Hydrogels
Mechanical stretch
Stem cell
in vitro devices

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10.1016/j.medntd.2023.100220

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title = "In vitro cell stretching devices and their applications: From cardiomyogenic differentiation to tissue engineering",

abstract = "Mechanical stretch plays an important role in the control of cardiomyocyte behavior, as well as in the study of the mechanisms of cardiovascular function and pathology. The complexity involved in biological systems in vivo has created a need for better in vitro techniques, thus a variety of cell stretching devices have been developed for a deeper understanding of cellular responses to strain. In this review, we introduce the design, functionality, and characteristics of multiple types of cell stretching devices from two and three dimensions, then discuss the research progress of promoting cardiomyogenic differentiation of stem cells by external stretching and its application in cardiac tissue engineering.",

keywords = "Cardiomyogenic differentiation, Hydrogels, Mechanical stretch, Stem cell, in vitro devices",

author = "Jiangtao Zhao and Fanzhe Meng and Jiayi Qian and Yan Huang and Yubo Fan",

note = "Publisher Copyright: {\textcopyright} 2023 The Authors",

year = "2023",

month = jun,

doi = "10.1016/j.medntd.2023.100220",

language = "英语",

volume = "18",

journal = "Medicine in Novel Technology and Devices",

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TY - JOUR

T1 - In vitro cell stretching devices and their applications

T2 - From cardiomyogenic differentiation to tissue engineering

AU - Zhao, Jiangtao

AU - Meng, Fanzhe

AU - Qian, Jiayi

AU - Huang, Yan

AU - Fan, Yubo

PY - 2023/6

Y1 - 2023/6

N2 - Mechanical stretch plays an important role in the control of cardiomyocyte behavior, as well as in the study of the mechanisms of cardiovascular function and pathology. The complexity involved in biological systems in vivo has created a need for better in vitro techniques, thus a variety of cell stretching devices have been developed for a deeper understanding of cellular responses to strain. In this review, we introduce the design, functionality, and characteristics of multiple types of cell stretching devices from two and three dimensions, then discuss the research progress of promoting cardiomyogenic differentiation of stem cells by external stretching and its application in cardiac tissue engineering.

AB - Mechanical stretch plays an important role in the control of cardiomyocyte behavior, as well as in the study of the mechanisms of cardiovascular function and pathology. The complexity involved in biological systems in vivo has created a need for better in vitro techniques, thus a variety of cell stretching devices have been developed for a deeper understanding of cellular responses to strain. In this review, we introduce the design, functionality, and characteristics of multiple types of cell stretching devices from two and three dimensions, then discuss the research progress of promoting cardiomyogenic differentiation of stem cells by external stretching and its application in cardiac tissue engineering.

KW - Cardiomyogenic differentiation

KW - Hydrogels

KW - Mechanical stretch

KW - Stem cell

KW - in vitro devices

UR - https://www.scopus.com/pages/publications/85149728675

U2 - 10.1016/j.medntd.2023.100220

DO - 10.1016/j.medntd.2023.100220

M3 - 文献综述

AN - SCOPUS:85149728675

SN - 2590-0935

VL - 18

JO - Medicine in Novel Technology and Devices

JF - Medicine in Novel Technology and Devices

M1 - 100220

ER -

In vitro cell stretching devices and their applications: From cardiomyogenic differentiation to tissue engineering

Abstract

Keywords

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