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Identification of important nodes in artificial bio-molecular networks

  • Pei Wang
  • , Xinghuo Yu
  • , Jinhu Lu
  • , Aimin Chen
  • Henan University
  • Royal Melbourne Institute of Technology University
  • Southeast University, Nanjing
  • Chinese Academy of Sciences

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Identification of important nodes is an emerging hot topic in complex networks over the last few decades. The so-called important nodes are hub, influential nodes, leaders, and so on. To characterize the importance of nodes, various indexes are introduced in complex networks, such as degree, closeness, betweenness, k-shell, and principal component analysis based on the adjacency matrix. By using the above indexes and multivariate statistical analysis technique, this paper aims at developing a new approach to identify the important nodes in artificial bio-molecular networks generated from the duplication-divergence (DD) model. In particular, the statistical characteristics of important nodes are also investigated. The above results shed light on the potential real-world applications in bio-molecular networks, such as deducing the genes related to the specific disease.

Original languageEnglish
Title of host publication2014 IEEE International Symposium on Circuits and Systems, ISCAS 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1267-1270
Number of pages4
ISBN (Print)9781479934324
DOIs
StatePublished - 2014
Externally publishedYes
Event2014 IEEE International Symposium on Circuits and Systems, ISCAS 2014 - Melbourne, VIC, Australia
Duration: 1 Jun 20145 Jun 2014

Publication series

NameProceedings - IEEE International Symposium on Circuits and Systems
ISSN (Print)0271-4310

Conference

Conference2014 IEEE International Symposium on Circuits and Systems, ISCAS 2014
Country/TerritoryAustralia
CityMelbourne, VIC
Period1/06/145/06/14

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