Highly sensitive nonenzymatic glucose sensor based on electrospun copper oxide-doped nickel oxide composite microfibers

Fei Cao; Shu Guo; Huiyan Ma; Guocheng Yang; Shengxue Yang; Jian Gong

doi:10.1016/j.talanta.2011.09.003

Highly sensitive nonenzymatic glucose sensor based on electrospun copper oxide-doped nickel oxide composite microfibers

Fei Cao
, Shu Guo
, Huiyan Ma
, Guocheng Yang
, Shengxue Yang
, Jian Gong^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

80 Scopus citations

Abstract

An improved nonenzymatic glucose sensor based on copper oxide-doped nickel oxide composite microfibers (CuO-NiO-MFs) modified fluorine tin oxide (FTO) electrode was prepared by electrospinning and calcination technologies without using any immobilization. The results of cyclic voltammetry (CV) and chronoamperometry demonstrated that the CuO-NiO-MFs modified electrode displayed much higher electrocatalytic activity than the nickel oxide microfibers (NiO-MFs) modified electrode toward glucose. The nonenzymatic glucose sensor based on CuO-NiO-MFs showed the highest sensitivity of 3165.53 μA mM ^-1 cm^-2 with the lowest detection limit of 1 × 10^-9 M (signal/noise ratio (S/N) = 3) in the nonenzymatic glucose sensors that have been reported in the literature. Additionally, its application for detecting glucose concentration of human serum sample showed good agreement with the results obtained from automatic biochemical analyzer.

Original language	English
Pages (from-to)	214-220
Number of pages	7
Journal	Talanta
Volume	86
Issue number	1
DOIs	https://doi.org/10.1016/j.talanta.2011.09.003
State	Published - 30 Oct 2011
Externally published	Yes

Keywords

Copper oxide
Doped
Electrospinning microfibers
Glucose sensor
Nickel oxide

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10.1016/j.talanta.2011.09.003

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@article{c9e3f5341bd645609f6034674bcb8a81,

title = "Highly sensitive nonenzymatic glucose sensor based on electrospun copper oxide-doped nickel oxide composite microfibers",

abstract = "An improved nonenzymatic glucose sensor based on copper oxide-doped nickel oxide composite microfibers (CuO-NiO-MFs) modified fluorine tin oxide (FTO) electrode was prepared by electrospinning and calcination technologies without using any immobilization. The results of cyclic voltammetry (CV) and chronoamperometry demonstrated that the CuO-NiO-MFs modified electrode displayed much higher electrocatalytic activity than the nickel oxide microfibers (NiO-MFs) modified electrode toward glucose. The nonenzymatic glucose sensor based on CuO-NiO-MFs showed the highest sensitivity of 3165.53 μA mM -1 cm-2 with the lowest detection limit of 1 × 10-9 M (signal/noise ratio (S/N) = 3) in the nonenzymatic glucose sensors that have been reported in the literature. Additionally, its application for detecting glucose concentration of human serum sample showed good agreement with the results obtained from automatic biochemical analyzer.",

keywords = "Copper oxide, Doped, Electrospinning microfibers, Glucose sensor, Nickel oxide",

author = "Fei Cao and Shu Guo and Huiyan Ma and Guocheng Yang and Shengxue Yang and Jian Gong",

year = "2011",

month = oct,

day = "30",

doi = "10.1016/j.talanta.2011.09.003",

language = "英语",

volume = "86",

pages = "214--220",

journal = "Talanta",

issn = "0039-9140",

publisher = "Elsevier B.V.",

number = "1",

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TY - JOUR

T1 - Highly sensitive nonenzymatic glucose sensor based on electrospun copper oxide-doped nickel oxide composite microfibers

AU - Cao, Fei

AU - Guo, Shu

AU - Ma, Huiyan

AU - Yang, Guocheng

AU - Yang, Shengxue

AU - Gong, Jian

PY - 2011/10/30

Y1 - 2011/10/30

N2 - An improved nonenzymatic glucose sensor based on copper oxide-doped nickel oxide composite microfibers (CuO-NiO-MFs) modified fluorine tin oxide (FTO) electrode was prepared by electrospinning and calcination technologies without using any immobilization. The results of cyclic voltammetry (CV) and chronoamperometry demonstrated that the CuO-NiO-MFs modified electrode displayed much higher electrocatalytic activity than the nickel oxide microfibers (NiO-MFs) modified electrode toward glucose. The nonenzymatic glucose sensor based on CuO-NiO-MFs showed the highest sensitivity of 3165.53 μA mM -1 cm-2 with the lowest detection limit of 1 × 10-9 M (signal/noise ratio (S/N) = 3) in the nonenzymatic glucose sensors that have been reported in the literature. Additionally, its application for detecting glucose concentration of human serum sample showed good agreement with the results obtained from automatic biochemical analyzer.

AB - An improved nonenzymatic glucose sensor based on copper oxide-doped nickel oxide composite microfibers (CuO-NiO-MFs) modified fluorine tin oxide (FTO) electrode was prepared by electrospinning and calcination technologies without using any immobilization. The results of cyclic voltammetry (CV) and chronoamperometry demonstrated that the CuO-NiO-MFs modified electrode displayed much higher electrocatalytic activity than the nickel oxide microfibers (NiO-MFs) modified electrode toward glucose. The nonenzymatic glucose sensor based on CuO-NiO-MFs showed the highest sensitivity of 3165.53 μA mM -1 cm-2 with the lowest detection limit of 1 × 10-9 M (signal/noise ratio (S/N) = 3) in the nonenzymatic glucose sensors that have been reported in the literature. Additionally, its application for detecting glucose concentration of human serum sample showed good agreement with the results obtained from automatic biochemical analyzer.

KW - Copper oxide

KW - Doped

KW - Electrospinning microfibers

KW - Glucose sensor

KW - Nickel oxide

UR - https://www.scopus.com/pages/publications/80755140191

U2 - 10.1016/j.talanta.2011.09.003

DO - 10.1016/j.talanta.2011.09.003

M3 - 文章

C2 - 22063533

AN - SCOPUS:80755140191

SN - 0039-9140

VL - 86

SP - 214

EP - 220

JO - Talanta

JF - Talanta

IS - 1

ER -

Highly sensitive nonenzymatic glucose sensor based on electrospun copper oxide-doped nickel oxide composite microfibers

Abstract

Keywords

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