High performance oxide functionalized nitrogen-doped mesocellular carbon foam for biosensor construction

Linpu Shi; Qiuming Gao; Yihua Wu

doi:10.1002/elan.200804469

High performance oxide functionalized nitrogen-doped mesocellular carbon foam for biosensor construction

Linpu Shi^*
, Qiuming Gao
, Yihua Wu

^*Corresponding author for this work

CAS - Shanghai Institute of Ceramics

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Nitrogen-doped mesocellular carbon foam (denoted as MCF-CN,) with high surface area and large pore volume was prepared and characterized in detail. The MCF-CN, was further functionalized by oxidation with HNO₃ (denoted as MCF - CN_x-O) in order to effectively improve its hydrophilicity and biocompatibility. Both MCF-CN, and MCF - CN_x-O were used for immobilization of Hb and design of electrochemical biosensors. The activity of Hb immobilized on MCF - CN_x-O is two times higher than that of Hb immobilized on MCF-CN, The Hb-MCF - CN_x-O-Nafion modified electrode displays fast response, high sensitivity and low detection limit to the detection of hydrogen peroxide. The sensitivity of Hb-MCF - CN _x-O-Nafion modified electrode (477 μA mM^-1 cm ^-2) is twice that of Hb-MCF - CN_x-Nafion modified electrode.

Original language	English
Pages (from-to)	715-722
Number of pages	8
Journal	Electroanalysis
Volume	21
Issue number	6
DOIs	https://doi.org/10.1002/elan.200804469
State	Published - Mar 2009
Externally published	Yes

Keywords

Hemoglobin
High performance
Immobilization
Nitrogen-doped mesocellular carbon foam

Access to Document

10.1002/elan.200804469

Cite this

@article{6b276591d0a8462e8cb14a10e485ce9d,

title = "High performance oxide functionalized nitrogen-doped mesocellular carbon foam for biosensor construction",

abstract = "Nitrogen-doped mesocellular carbon foam (denoted as MCF-CN,) with high surface area and large pore volume was prepared and characterized in detail. The MCF-CN, was further functionalized by oxidation with HNO3 (denoted as MCF - CNx-O) in order to effectively improve its hydrophilicity and biocompatibility. Both MCF-CN, and MCF - CNx-O were used for immobilization of Hb and design of electrochemical biosensors. The activity of Hb immobilized on MCF - CNx-O is two times higher than that of Hb immobilized on MCF-CN, The Hb-MCF - CNx-O-Nafion modified electrode displays fast response, high sensitivity and low detection limit to the detection of hydrogen peroxide. The sensitivity of Hb-MCF - CN x-O-Nafion modified electrode (477 μA mM-1 cm -2) is twice that of Hb-MCF - CNx-Nafion modified electrode.",

keywords = "Hemoglobin, High performance, Immobilization, Nitrogen-doped mesocellular carbon foam",

author = "Linpu Shi and Qiuming Gao and Yihua Wu",

year = "2009",

month = mar,

doi = "10.1002/elan.200804469",

language = "英语",

volume = "21",

pages = "715--722",

journal = "Electroanalysis",

issn = "1040-0397",

publisher = "Wiley-VCH Verlag",

number = "6",

}

TY - JOUR

T1 - High performance oxide functionalized nitrogen-doped mesocellular carbon foam for biosensor construction

AU - Shi, Linpu

AU - Gao, Qiuming

AU - Wu, Yihua

PY - 2009/3

Y1 - 2009/3

N2 - Nitrogen-doped mesocellular carbon foam (denoted as MCF-CN,) with high surface area and large pore volume was prepared and characterized in detail. The MCF-CN, was further functionalized by oxidation with HNO3 (denoted as MCF - CNx-O) in order to effectively improve its hydrophilicity and biocompatibility. Both MCF-CN, and MCF - CNx-O were used for immobilization of Hb and design of electrochemical biosensors. The activity of Hb immobilized on MCF - CNx-O is two times higher than that of Hb immobilized on MCF-CN, The Hb-MCF - CNx-O-Nafion modified electrode displays fast response, high sensitivity and low detection limit to the detection of hydrogen peroxide. The sensitivity of Hb-MCF - CN x-O-Nafion modified electrode (477 μA mM-1 cm -2) is twice that of Hb-MCF - CNx-Nafion modified electrode.

AB - Nitrogen-doped mesocellular carbon foam (denoted as MCF-CN,) with high surface area and large pore volume was prepared and characterized in detail. The MCF-CN, was further functionalized by oxidation with HNO3 (denoted as MCF - CNx-O) in order to effectively improve its hydrophilicity and biocompatibility. Both MCF-CN, and MCF - CNx-O were used for immobilization of Hb and design of electrochemical biosensors. The activity of Hb immobilized on MCF - CNx-O is two times higher than that of Hb immobilized on MCF-CN, The Hb-MCF - CNx-O-Nafion modified electrode displays fast response, high sensitivity and low detection limit to the detection of hydrogen peroxide. The sensitivity of Hb-MCF - CN x-O-Nafion modified electrode (477 μA mM-1 cm -2) is twice that of Hb-MCF - CNx-Nafion modified electrode.

KW - Hemoglobin

KW - High performance

KW - Immobilization

KW - Nitrogen-doped mesocellular carbon foam

UR - https://www.scopus.com/pages/publications/64249116692

U2 - 10.1002/elan.200804469

DO - 10.1002/elan.200804469

M3 - 文章

AN - SCOPUS:64249116692

SN - 1040-0397

VL - 21

SP - 715

EP - 722

JO - Electroanalysis

JF - Electroanalysis

IS - 6

ER -

High performance oxide functionalized nitrogen-doped mesocellular carbon foam for biosensor construction

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this