Hemoglobin-titanate composite based biosensor for the amperometric determination of hydrogen peroxide in acidic medium

Yihua Wu; Qiuming Gao; Linpu Shi; Lu Gao

doi:10.1002/elan.200804520

Hemoglobin-titanate composite based biosensor for the amperometric determination of hydrogen peroxide in acidic medium

Yihua Wu^*
, Qiuming Gao
, Linpu Shi
, Lu Gao

^*Corresponding author for this work

CAS - Shanghai Institute of Ceramics

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

A hemoglobin-titanate composite based biosensor was chosen for determination of H₂O₂ in an acidic medium. CV results of the Hb-titanate modified pyrolytic graphite electrode showed a pair of well-defined, quasi-reversible redox peaks centered at - 246 mV (vs. Ag/AgCl) in a pH 5.0 HAc-NaAc buffer solution. The modified electrode exhibited good electrocatalytic response for monitoring H₂O₂ and had a large linear detection range from 20 μM to 3.2 mM with a detection limit of 8 μM (S/N = 3) and a sensitivity of 29.7 mA M^-1 cm^-2 in the pH 5.0 solution. The biosensor also possessed good long term storage stability.

Original language	English
Pages (from-to)	904-908
Number of pages	5
Journal	Electroanalysis
Volume	21
Issue number	8
DOIs	https://doi.org/10.1002/elan.200804520
State	Published - Apr 2009
Externally published	Yes

Keywords

Acidic medium
Biosensor
Hemoglobin
Hydrogen peroxide
Layered titanate

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10.1002/elan.200804520

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title = "Hemoglobin-titanate composite based biosensor for the amperometric determination of hydrogen peroxide in acidic medium",

abstract = "A hemoglobin-titanate composite based biosensor was chosen for determination of H2O2 in an acidic medium. CV results of the Hb-titanate modified pyrolytic graphite electrode showed a pair of well-defined, quasi-reversible redox peaks centered at - 246 mV (vs. Ag/AgCl) in a pH 5.0 HAc-NaAc buffer solution. The modified electrode exhibited good electrocatalytic response for monitoring H2O2 and had a large linear detection range from 20 μM to 3.2 mM with a detection limit of 8 μM (S/N = 3) and a sensitivity of 29.7 mA M-1 cm-2 in the pH 5.0 solution. The biosensor also possessed good long term storage stability.",

keywords = "Acidic medium, Biosensor, Hemoglobin, Hydrogen peroxide, Layered titanate",

author = "Yihua Wu and Qiuming Gao and Linpu Shi and Lu Gao",

year = "2009",

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doi = "10.1002/elan.200804520",

language = "英语",

volume = "21",

pages = "904--908",

journal = "Electroanalysis",

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TY - JOUR

T1 - Hemoglobin-titanate composite based biosensor for the amperometric determination of hydrogen peroxide in acidic medium

AU - Wu, Yihua

AU - Gao, Qiuming

AU - Shi, Linpu

AU - Gao, Lu

PY - 2009/4

Y1 - 2009/4

N2 - A hemoglobin-titanate composite based biosensor was chosen for determination of H2O2 in an acidic medium. CV results of the Hb-titanate modified pyrolytic graphite electrode showed a pair of well-defined, quasi-reversible redox peaks centered at - 246 mV (vs. Ag/AgCl) in a pH 5.0 HAc-NaAc buffer solution. The modified electrode exhibited good electrocatalytic response for monitoring H2O2 and had a large linear detection range from 20 μM to 3.2 mM with a detection limit of 8 μM (S/N = 3) and a sensitivity of 29.7 mA M-1 cm-2 in the pH 5.0 solution. The biosensor also possessed good long term storage stability.

AB - A hemoglobin-titanate composite based biosensor was chosen for determination of H2O2 in an acidic medium. CV results of the Hb-titanate modified pyrolytic graphite electrode showed a pair of well-defined, quasi-reversible redox peaks centered at - 246 mV (vs. Ag/AgCl) in a pH 5.0 HAc-NaAc buffer solution. The modified electrode exhibited good electrocatalytic response for monitoring H2O2 and had a large linear detection range from 20 μM to 3.2 mM with a detection limit of 8 μM (S/N = 3) and a sensitivity of 29.7 mA M-1 cm-2 in the pH 5.0 solution. The biosensor also possessed good long term storage stability.

KW - Acidic medium

KW - Biosensor

KW - Hemoglobin

KW - Hydrogen peroxide

KW - Layered titanate

UR - https://www.scopus.com/pages/publications/65349167318

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DO - 10.1002/elan.200804520

M3 - 文章

AN - SCOPUS:65349167318

SN - 1040-0397

VL - 21

SP - 904

EP - 908

JO - Electroanalysis

JF - Electroanalysis

IS - 8

ER -

Hemoglobin-titanate composite based biosensor for the amperometric determination of hydrogen peroxide in acidic medium

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Keywords

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