TY - GEN
T1 - Fluorescence molecular tomography with optimal radon transform based surface reconstruction
AU - Liu, Xin
AU - Wang, Daifa
AU - Bai, Jing
PY - 2009
Y1 - 2009
N2 - Full angle non-contact fluorescence molecular tomography allows acquiring large data sets from complete angles, and simplifies the experimental setups. Accurately extracting animal surface is important for this kind of imaging systems. However, in in-vivo experiments, mouse breath movements and mechanical errors will influence the surface reconstruction. An optimal radon transform based surface reconstruction method is proposed to handle these two factors. The proposed method uses a line searching method to minimize the mismatch between the reconstructed 3D surface and the projected silhouettes at different angles. Therefore, the proposed method generates the optimal 3D surface compared to other methods based on radon transform. Results show that the mean mismatch of 3D surface generated is less than two CCD pixels (0.154 mm) in in-vivo experiments. In-vivo fluorescence molecular tomography is also performed to demonstrate the efficiency of the proposed method.
AB - Full angle non-contact fluorescence molecular tomography allows acquiring large data sets from complete angles, and simplifies the experimental setups. Accurately extracting animal surface is important for this kind of imaging systems. However, in in-vivo experiments, mouse breath movements and mechanical errors will influence the surface reconstruction. An optimal radon transform based surface reconstruction method is proposed to handle these two factors. The proposed method uses a line searching method to minimize the mismatch between the reconstructed 3D surface and the projected silhouettes at different angles. Therefore, the proposed method generates the optimal 3D surface compared to other methods based on radon transform. Results show that the mean mismatch of 3D surface generated is less than two CCD pixels (0.154 mm) in in-vivo experiments. In-vivo fluorescence molecular tomography is also performed to demonstrate the efficiency of the proposed method.
UR - https://www.scopus.com/pages/publications/77950976428
U2 - 10.1109/IEMBS.2009.5334178
DO - 10.1109/IEMBS.2009.5334178
M3 - 会议稿件
C2 - 19964524
AN - SCOPUS:77950976428
SN - 9781424432967
T3 - Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
SP - 1404
EP - 1407
BT - Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society
PB - IEEE Computer Society
T2 - 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
Y2 - 2 September 2009 through 6 September 2009
ER -