Field-swept magnetic particle spectroscopy using a transverse DC field

Yanjun Liu; Xin Feng; Haoran Zhang; Sijia Liu; Guanghui Li; Yu An; Hui Hui; Jie Tian

doi:10.18416/IJMPI.2023.2303047

Field-swept magnetic particle spectroscopy using a transverse DC field

Yanjun Liu
, Xin Feng^*
, Haoran Zhang
, Sijia Liu
, Guanghui Li
, Yu An
, Hui Hui^*
, Jie Tian^*

^*Corresponding author for this work

School of Engineering Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

The transverse magnetization of magnetic nanoparticles (MNPs) induced by a DC field perpendicular to the AC field is of increasing interest in magnetic particle imaging (MPI) and magnetic particle spectroscopy (MPS). It can be used to improve the image quality in MPI and to enhance the sensitivity of MPS without direct feedthrough interference. In this work, we developed a field-swept MPS to observe the response curve of the transverse magnetization by varying the transverse DC field amplitude, and reported a new metric to characterize the nonlinear properties of MNPs, called DCM (the DC field amplitude at the maximum harmonic amplitude). Two commercial MNPs (synomag®-70 and synomag®-50) were investigated. The experimental results show that the DCM is different for the two MNPs and independent of the concentration of MNPs. In addition, the DCM was positively correlated with the viscosity of the sample solvent, which further indicates a correlation with Brownian relaxation.

Original language	English
Article number	2303047
Journal	International Journal on Magnetic Particle Imaging
Volume	9
DOIs	https://doi.org/10.18416/IJMPI.2023.2303047
State	Published - 2023

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title = "Field-swept magnetic particle spectroscopy using a transverse DC field",

abstract = "The transverse magnetization of magnetic nanoparticles (MNPs) induced by a DC field perpendicular to the AC field is of increasing interest in magnetic particle imaging (MPI) and magnetic particle spectroscopy (MPS). It can be used to improve the image quality in MPI and to enhance the sensitivity of MPS without direct feedthrough interference. In this work, we developed a field-swept MPS to observe the response curve of the transverse magnetization by varying the transverse DC field amplitude, and reported a new metric to characterize the nonlinear properties of MNPs, called DCM (the DC field amplitude at the maximum harmonic amplitude). Two commercial MNPs (synomag{\textregistered}-70 and synomag{\textregistered}-50) were investigated. The experimental results show that the DCM is different for the two MNPs and independent of the concentration of MNPs. In addition, the DCM was positively correlated with the viscosity of the sample solvent, which further indicates a correlation with Brownian relaxation.",

author = "Yanjun Liu and Xin Feng and Haoran Zhang and Sijia Liu and Guanghui Li and Yu An and Hui Hui and Jie Tian",

note = "Publisher Copyright: {\textcopyright} 2023 Liu et al.; licensee Infinite Science Publishing GmbH {\textcopyright} 2023 Infinite Science Publishing.",

year = "2023",

doi = "10.18416/IJMPI.2023.2303047",

language = "英语",

volume = "9",

journal = "International Journal on Magnetic Particle Imaging",

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publisher = "Infinite Science Publishing",

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TY - JOUR

T1 - Field-swept magnetic particle spectroscopy using a transverse DC field

AU - Liu, Yanjun

AU - Feng, Xin

AU - Zhang, Haoran

AU - Liu, Sijia

AU - Li, Guanghui

AU - An, Yu

AU - Hui, Hui

AU - Tian, Jie

PY - 2023

Y1 - 2023

N2 - The transverse magnetization of magnetic nanoparticles (MNPs) induced by a DC field perpendicular to the AC field is of increasing interest in magnetic particle imaging (MPI) and magnetic particle spectroscopy (MPS). It can be used to improve the image quality in MPI and to enhance the sensitivity of MPS without direct feedthrough interference. In this work, we developed a field-swept MPS to observe the response curve of the transverse magnetization by varying the transverse DC field amplitude, and reported a new metric to characterize the nonlinear properties of MNPs, called DCM (the DC field amplitude at the maximum harmonic amplitude). Two commercial MNPs (synomag®-70 and synomag®-50) were investigated. The experimental results show that the DCM is different for the two MNPs and independent of the concentration of MNPs. In addition, the DCM was positively correlated with the viscosity of the sample solvent, which further indicates a correlation with Brownian relaxation.

AB - The transverse magnetization of magnetic nanoparticles (MNPs) induced by a DC field perpendicular to the AC field is of increasing interest in magnetic particle imaging (MPI) and magnetic particle spectroscopy (MPS). It can be used to improve the image quality in MPI and to enhance the sensitivity of MPS without direct feedthrough interference. In this work, we developed a field-swept MPS to observe the response curve of the transverse magnetization by varying the transverse DC field amplitude, and reported a new metric to characterize the nonlinear properties of MNPs, called DCM (the DC field amplitude at the maximum harmonic amplitude). Two commercial MNPs (synomag®-70 and synomag®-50) were investigated. The experimental results show that the DCM is different for the two MNPs and independent of the concentration of MNPs. In addition, the DCM was positively correlated with the viscosity of the sample solvent, which further indicates a correlation with Brownian relaxation.

UR - https://www.scopus.com/pages/publications/85151498870

U2 - 10.18416/IJMPI.2023.2303047

DO - 10.18416/IJMPI.2023.2303047

M3 - 文章

AN - SCOPUS:85151498870

SN - 2365-9033

VL - 9

JO - International Journal on Magnetic Particle Imaging

JF - International Journal on Magnetic Particle Imaging

M1 - 2303047

ER -

Field-swept magnetic particle spectroscopy using a transverse DC field

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