Fast-specific tomography imaging via cerenkov emission

Purpose: Development of more tumor-specific radiopharmaceuticals is not enough; to understand the disease, we must study data modeling. Although fluoro-18-deoxyglucose positron emission tomography can map a multi-peak distribution of trace radioisotopes, optical tomography should also be able to redirect the distribution. Procedures: Multi-view image acquisition of small animals injected with 2-deoxy-2-[ ¹⁸F]fluoro-D-glucose began with X-ray computed tomography scanning and Cerenkov luminescence imaging. After fusion processing, utilization of the geometric row scaling and L _1/2 regularization operator effectively generates in vivo Cerenkov luminescence tomography images with the SP ₃ forward model. Results: The identification is confirmed by the comparison between tumor-specific tomography from Cerenkov emission and the radioactivity measured in vitro. Conclusion: The proposed technique can quickly localize the mobility of radionuclides and uptake by organs, which provides an imaging methodology in oncology.