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Fast orthogonal search method for modeling nonlinear hemodynamic response in fMRI

  • Xingfeng Li
  • , Jie Tian*
  • , Xiaoxiang Wang
  • , Jianping Dai
  • , Lin Ai
  • *Corresponding author for this work
  • CAS - Institute of Automation
  • Capital Medical University

Research output: Contribution to journalConference articlepeer-review

Abstract

This study presents a fast orthogonal search (FOS) method for modeling fMRI time series. Based on the system identification theory, an orthogonalization procedure to model the fMRI time series is described. FOS method does not require equally space data, and can resolve sinusoidal frequencies much more closely than Fourier transform method. After the time series are modeled by means of the FOS, F-test is employed to detect the activation regions. Eight volunteers' data were collected to validate the proposed method. The results demonstrate the feasibility of the proposed method.

Original languageEnglish
Pages (from-to)219-226
Number of pages8
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume5369
DOIs
StatePublished - 2004
Externally publishedYes
EventMedical Imaging 2004: Physiology, Function, and Structure from Medical Images - San Diego, CA, United States
Duration: 15 Feb 200417 Feb 2004

Keywords

  • Bold-fMRI
  • Fast orthogonal search
  • Nonlinear system identification

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